Lecture 4- Mood Disorders Flashcards

1
Q

Syndrome

A

Regular coexistence of symptoms

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2
Q

DSM Disorder Criteria

A

Syndrome, loss of function, time course, no better explination

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3
Q

Major Depressive Disorder Symptoms

A

Need 5+ and 1 *
Depressed mood*
Loss of interest or pleasure*
Insomnia or hypersomnia
Psychomotor agitation or retardation
Fatigue or loss of energy
Feelings of worthlessness or excessive guilt
Poor concentration or indecisiveness
Suicidal ideation

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4
Q

Major Depressive Disorder Diagnostic Criteria

A

Distress or impairment in social, occupational, or other functions
5+ symptoms
Symptoms last for at least 2 weeks

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5
Q

Depression Throughout Development

A

Infancy- Anaclitic Depression- Apathetic and lack of expression
Toddler (1-2)- Aggression, hyperactive
Preschoolers- Irritable, social withdrawal
School age- Withdrawal, avoid play, not talking with family, negative beliefs about the world
Adolescents-
12- Pessimistic, sleep problems, decreased appetitie
17- Nightmares, suicidal ideation

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6
Q

Abraham-Freud Model of Depression

A

Aggression turned inward becomes depression; Loss of self esteem

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7
Q

Object-Loss Model

A

Spitz and Bowlby
Separation and disruption of attachment bonds
Insecure caretaker relationship or atmosphere without love

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8
Q

Negative Cognitive Triad

A

Beck
Negative views of self, past, and future
Worthlessness, helplessness, and hoplessness

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9
Q

Learned Helplessness

A

Seligman
False belief that actions have no impact on life events

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10
Q

Loss of Reinforcement

A

Lazarus and Lewinsohn
Lack of positive reinforcements will cause depression

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11
Q

Biological Model of Depression

A

Genetic factors and neurophysical theories
Intrinsic factors

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12
Q

Electroconvulsive Therapy (ECT)

A

Passage of electrical current through brain to create artificial Grand-Mal seizure for treatment-resistant depression

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13
Q

ECT Procedure

A

2 electrodes placed on scalp (both RH) and current passed between them in 1 second intervals until seizure is confirmed and lasts for 30s-1min
Patient is unconscious, paralyzed, and closely monitored
2-3 sessions per week for 6-12 sessions

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14
Q

ECT Indications

A

Treatment resistance severe depression
Delusions, insomnia, loss of appetite, total loss of pleasure

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15
Q

ECT Risks

A

Reaction to anesthesia, cardiac arrest, further seizures or brain damage
Risk worsening depression or suicide without treatment

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16
Q

Post Partum Depression

A

Non-psychotic depressive episode that begins prior to or after delivery and continues into post-partum period
Based on MDD criteria, only needs to last 1 week

17
Q

Postpartum risk factors

A

Hormonal changes after birth
Low income and social supports
Poor caretaker relationships
History of mood disorders

18
Q

Postpartum treatments

A

Interpersonal Psychotherapy
Cognitive Behavioral Therapy
Antidepressants (Tricyclic and SSRI)

19
Q

Postpartum Blues

A

Less severe and more common postpartum depression that is benign and short-lived

20
Q

Post partum psychosis

A

Severe and rare disorder with sudden onset and rapid depressive and psychotic symptoms

21
Q

Postpartum Disorders Prevalence Rates

A

Postpartum blues- 30-75%
Postpartum depression- 13%
Postpartum Psychosis- <1%

22
Q

Manic Episode Symptoms

A

Inflated self-esteem or grandiosity
Decreased sleep
Pressure speech or more talkative
Racing thoughts
Distractibility
Goal-directed activity
Pleasurable activities with consequences

23
Q

Manic Episode Criteria

A

3+ symptoms
Distress or impairment
Time course (Mania- 1+ week; Hypomania- 4+ days)

24
Q

Bipolar I

A

1+ manic episodes present

25
Bipolar II
1+ depressive episode and 1+ hypomanic episode No full mania
26
Dysthymia "Persistent Depressive Disorder"
Depressive symptoms not severe enough to meet MDD criteria Last for 2+ years a majority of time
27
Cyclothymia
Numerous periods of hypomania and depression for 2+ years but not meeting criteria for full bipolar diagnosis Often begins in adolescence and 15-50% develop into bipolar
28
Relationship between mood disorders
Unipolar MDD > Dysthymia Bipolar BPD > Cyclothymia
29
Lifetime prevalence rates
MDD- 10-25% women; 5-12% men Dysthymia- 6% BPD- 1% Cyclothymia- 1%
30
Ketamine Treatments
(es)Ketamine nasal spray in low doses has antidepressant and anti-suicide effects with functional reorganization in the brain Fast acting (within 2 hours) and long lasting (up to 7 days) Uses as adjunctive therapy Well tolerated short-term but may have severe side-effects long term
31
Associations with Death
Sleep Reunion Happiness and Heaven Lifelessness No pain or trouble
32
Suicide Risk Factors
Age (Adolescent and elderly) Sex (male) Race (white and native american)
33
Common Suicide Trigger events
Family problems Loss Health change Pressure to succeed
34
Recipe for suicide risk
Negative affect Method Alcohol and drug use Trigger event Practice
35
Interventions
Create opportunities for honesty and change to determine and remove method
36
Suicide Treatment
Start with antidepressants and follow up with psychotherapy