Lecture 30 - Introduction to immunology and the immune system Flashcards
What are the overall components of the immune system that defend the body against disease?
Organs, cells, antibodies
What is the name for a microbe that causes disease?
Pathogen
What are primary lymphoid organs?
Organs that produce white blood cells/lymphocytes
What are the two primary lymphoid organs?
Bone marrow, thymus
What is the function of bone marrow?
Source of stem cells that develop into cells of the innate and adaptive immune responses.
What is the function of the thymus?
Produces T cells (T lymphocytes) and ‘teach’ them what to react to and how. They learn not to react to self in order to prevent auto-immunity.
What are secondary lymphoid organs?
Sites where immune responses are initiated
What are the two secondary lymphoid organs?
Spleen, lymph nodes
What is the function of the spleen?
Site of initiation of white blood cell immune responses to blood-borne pathogens. Filters blood to remove old cells.
What are lymph nodes?
Nodes along lymphatic vessels where lymph fluid from blood and tissue is filtered. Site of initiation of immune responses.
What is the immune system?
An organised system of organs, cells and molecules that interact together to defend the body against disease – eg pathogenic microorganisms and cancer
The immune system is composed of which 3 things?
Organs, cells and molecules
What are the 3 layers of defense?
Chemical and physical barriers
Innate “arm”
Adaptive “arm”