Lecture 27 - Neuro-endocrine connection - the hypothalamus and pituitary gland Flashcards
What hormones are secreted by the thyroid gland?
Thyroid hormone (T3, T4) and calcitonin
What is the location of the thyroid gland?
On anterior and lateral surfaces of the trachea, inferior to the larynx
What is the structure of the thyroid gland?
Composed of small spherical sacs (follicles) surrounded by follicular cells. Clear/C cells lie in clusters between follicles
What is the function of the follicular cells of the thyroid?
Synthesis and storage of thyroid hormones
Where is the hormone calcitonin made?
In the Clear/C cells of the thyroid gland.
What type of cell are follicular cells?
Epithelial cells
What type of hormone are thyroid hormones?
Lipid-soluble hormones
How are thyroid hormones T3 and T4 made?
Iodine enters follicular cells and forms complexes with tyrosine from thyroglobulin proteins (TGB) made in the thyroid follicles.
What is the structure of T3 hormone?
3 iodine (I) surrounding a tyrosine (Y)
What is the structure of a T4 hormone?
4 iodine (I) surrounding a tyrosine (Y)