LECTURE 20: Neurological Diseases I

Question 1

What is avian encephalomyelitis?

Answer 1

AE ssRNA virus that is non-enveloped

Question 2

AE is _____ only.

Answer 2

Chicken (young birds)

Question 3

AE has what kind of transmission?

Answer 3

Vertical (hen to chick)

Question 4

What does viremic mean? What disease causes this?

Answer 4

Virus in the blood
AE

Question 5

What are clinical signs of AE?

Answer 5

Ataxia, fine tremors, drop in egg production progression to paralysis

Question 6

What is the common name of AE?

Answer 6

Epidemic Tremor

Question 7

Why do you vaccinate hens for AE?

Answer 7

To protect the chicks

Question 8

What is the dead giveaway for AE?

Answer 8

Tremors of the head

Question 9

What sampling will you do for AE?

Answer 9

1. Serology
2. PCR
3. Virus Isolation
4. Histopathology
   **Brain for sampling

Question 10

What does the prevention and treatment look like for AE?

Answer 10

NO TREATMENT
Vaccination

Question 11

What is Marek’s disease?

Answer 11

Herpesvirus, dsDNA enveloped

Question 12

What serotype of Marek’s disease is pathogenicc?

Answer 12

Serotype 1 (pathogenic)

Question 13

What are the clinical signs of neurological mareks?

Answer 13

Transient paralysis
Peripheral nerve paralysis
Blindness
Depression and immunosuppression

Question 14

Mareks disease effects what window age of birds?

Answer 14

Before 16 wks but not right away when they are young

Question 15

What kinds of cells does mareks affect?

Answer 15

B cells and develops latency in t cells

Question 16

Where is the infected virus produced in mareks?

Answer 16

Feather follicle epithelium (FFE)

Question 17

What are the forms of neurological lesions in a mareks necropsy?

Answer 17

1. Nerve degenerative lesions
2. Nerve lymphocytic inflammation
3. Swollen nerves, discoloration and loss of cross strainsn

Question 18

What is a necropsy giveaway of mareks?

Answer 18

Huge ass nerves

Question 19

What samples should you take for mareks?

Answer 19

1. PCR
2. Histopathology

Question 20

How do you prevent and control mareks?

Answer 20

Vaccination as early as possible

Question 21

What is the best vax for mareks?

Answer 21

Serotype 1 vaccine

Question 22

What are the four necropsy lesion patterns?

Answer 22

1. Visceral
2. Cutaneous
3. Ocular
4. Neural

Question 23

What is arbovirus?

Answer 23

Virus that is caused by insects

Question 24

What is botulism? (limberneck)

Answer 24

Gram positive bacteria that causes limp neck (super resistant)

Question 25

Botulism occurs in what ____.

Answer 25

Ducks occasionally domestic poultry

Question 26

What are the clinical signs to botulism?

Answer 26

Drowsiness, weakness, and progressive loss of control of legs, wings, neck, paralysis of 3rd eyelid, feather loss

Question 27

What is a rule out process for botulism?

Answer 27

Wont see anything physically and wont see anything on the histo (crop filled with gross stuff0

Question 28

What is the only test for botulism?

Answer 28

Take blood samples (inject into mice)