LEC: Immune System/diseases Flashcards
What are six antigenic substances?
Bacteria, viruses, toxins, transplanted tissue, pollen, food protiens
What does the immune system do?
Eliminate foreign substances introduced to the body to prevent harmful effects
What are the two components of the immune system?
Nonspecific and specific immune system
What does the non specific immune system do?
Prevents initial invasion by the antigen by using physical barriers and phagocytosis
What does the specific immune system do?
Controls the humoral immune system and the cell mediated immune response
What does the humoral immune system do?
Involves the production of AG specific antibodies by B-lymphocytes
What are six antibody classes? (IGAME)
IgI IgG IgA IgM IgE
What removes the extrasolar Ag’s?
Antibodies
What does the cell mediated immune response do?
Involves the production of AG specific T-lymphocytes
What is immunization?
The administration of an AG to induce resistance to infection
How can immunization be achieved? 2
Exposeur to infectious disease
Vaccination
What are three types of vaccines?
Killed/inactivated
Modified live/attenuated
Recombinant/genetically engineered
How can temporary immunization be achieved?
By antibody administration through passive immunity or immunoglobulin injection
What is anaphylaxis?
Binding of an AG to IgE covered mast cells or basophils causing them to release chemical mediators like histamine
What are five possible Ag’s for anaphylaxis?
Vaccines Drus Pollens/molds Food ingredients Insect bites
What are 7 symptoms of anaphylaxis?
Shock Hives Nasal/ocular discharge Asthma V D Dermatitis
What are autoimmune diseases?
Antibodies are formed against the animals own cells causing destruction
What are for examples of autoimmune diseases
Autoimmune hemolytic anemia
Autoimmune thrombocytopenia
Pemphigus
Myasthenia gravis
What is immunodeficiency?
Lack of the immune system components to provide immunity
What is an example of immunodeficiency?
Combined immunodefficiency in horses
Most diagnostic tests are based on what for the immune system?
Based on the humoral immune systems respone to AG
What is serology?
The science of detection and measurement of abs or Ag’s.
What are three types of serologic tests for infectious diseases?
Enzyme linked immuno sorbet assay
Latex agglutination
Immuno diffusion
