Lec 5 Intro to Rheum

Question 1

Articular collagen fibers are anchored to the _____ bone. They form a meshwork that entraps ____ aggregates

Answer 1

subchondral

proteglycan

Question 2

proteoglycans consist of _____ that are very hydro____

Answer 2

glycosaminoglycans; hydrophillic

Question 3

What gives cartilage its elasticity?

Answer 3

pressure of bound water

Question 4

What supplies nutrition to the chondrocytes?

Answer 4

synovial fluid produced by synovial membrane

Question 5

Rheumatoid arthritis is a disease of what anatomical site?

Answer 5

synovial membrane

Question 6

Rank in order of most acute onset to most gradual:

fibromyalgia, gout, RA

Answer 6

gout (minutes)–> RA (days to weeks) –> fibromyalgia (years)

Question 7

constitutional symptoms such as fever, morning stiffness, and malaise imply ____ diseases such as ____ and _____

Answer 7

systemic;

lupus, RA

Question 8

Gout responds remarkably to ____

fibromyalgia responds to ____

Answer 8

NSAIDS;

excercise

Question 9

What does STL stand for, and what is it rated out of, in regards to physical examination?

Answer 9

Swelling
Tenderness
Limitation
all rated out of 0-4

Question 10

In inflammation, Hb and albumin levels _____

Answer 10

decrease