LATG 16 Pharma Flashcards
Pharma
therapeutic dose
a drug must be sufficient to produce the desired pharmacological effect without producing toxicity
Pharmacokinetics
study of the processes by which a drug or compound is handled by the body
ADME
Absorption
distribution metabolism and exctretion
Absorptions
ability of the drug to enter the bloodstream
shortest to longest peak effect routes of doses
IV < IP < IM < SC < PO
Why is clauvanate administered with amoxicillin
To overcome breakdown of the antibiotic
sulfonamides
sulfa drugs, are broad-spectrum antibiotics
Fluoroquinolones
potent broad-spectrum drugs used in multiple species for treating infections of E. coli, Salmonella spp, Shigella spp, et
Aminoglycosides
include neomycin, gentamicin, and kanamycin Gram-negative spectrum- inner ear and kidney toxicity
penicillin
mainly a Gram-positive spectrum of activity
Cephalosporins
treating Gram-positive organisms, particularly ones resistant to the penicillins
Nitroimidazoles
Metronidazole: is an antibiotic that can be used to treat infections of anaerobic bacteria and parasitic protozoa, such as Amoeba, Giardia, and Trichomonas.
Antifungal Drugs
used for treating systemic and superficial infection
Ivermectin
internally (nematodes) and externally (mites and lice) orally, parenterally, or topically
Fenbendazole
treat internal parasites—mainly nematodes. I
What are pyrethrins
insecticides
Which type of antibiotic is often added to the drinking water of immunosuppressed mice to prevent infection by Pneumocystis carinii
sulfonamide
In enterotoxemia, Clostridium difficile proliferates rapidly when the normal bacteria are killed by penicillin
True
A hamster was treated with penicillin to treat an infection caused by a gram-positive organism. The animal died the morning after the treatment. What is a cause of death that you should immediately consider?
A toxin secreted by <i>Clostridium difficile</i> killed the animal.
In which species is atropine not effective to reduce salivation under anesthesia
rabbits
Which species shows a manic excitement when given doses of morphine that cause depression in most other species
cats
When speaking of multimodal drug therapy, “modal” refers to different modes of:
action
Modal- mode-action