Lab 4 Notes - Blood Typing Flashcards

1
Q

What is blood typing based on?

A

Based on the antigens that are on red blood cells

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2
Q

What are antigens

A

Combinations of organic molecules

* Proteins, Glycoproteings, Glycolipids, Lipoproteins

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3
Q

Where are antigens located

A

On surface of red blood cell

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4
Q

What do antigens stimulate

A

Antibody production

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5
Q

What is an antibody

A

A protein that can bind to an antigen

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6
Q

When antibodies bind to antigens it causes what?

A

Agglutinogens - clumping

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7
Q

What happens when blood agglutinates

A

It causes a transfusion reaction

  • blood cells clump
  • vessels get clogged
  • red blood cells hemolyze (rupture)
  • hemoglobin is released and clot nephrons in kidneys
  • nephrons die causing kidney failure
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8
Q

If you have blood type A then you will have what antibodies

A

Anti-B antibodies

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9
Q

If you have blood type B then you will have what anitbodies

A

Anti- A antibodies

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10
Q

If you have blood type AB then you will have what antibodies, and are considered what specific type of blood type

A

You will have no antibodies

Universal Recipient

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11
Q

If you have blood type O then what antigens and antibodies do you have

A

You have no antigens

You have AB antibodies

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12
Q

In blood type testing is Anti B & Anti A antibodies are added to an unknown blood type and clumping happens only with Anti-B antibodies then what blood type is it?

A

Blood type B

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13
Q

In blood type testing is Anti B & Anti A antibodies are added to an unknown blood type and clumping happens only with Anti-A antibodies then what blood type is it?

A

Blood type A

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14
Q

In blood type testing is Anti B & Anti A antibodies are added to an unknown blood type and clumping happens with both antibodies then what blood type is it?

A

Blood type AB

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15
Q

In blood type testing is Anti B & Anti A antibodies are added to an unknown blood type and clumping does not happen then what blood type is it?

A

Blood type O

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16
Q

What blood type is the universal donor

A

Blood type O

17
Q

What is the Rh factor

A

another antigen present on red blood cells that causes blood types to be Rh postive or Rh negative

18
Q

If you are Rh + then do you have the Rh antibodies

A

No if you did you would aggutinate your own blood causing kidney failure and death

19
Q

If dad is Rh + and mom is Rh + is there a risk for an Rh factor during delivery

A

No the baby will have Rh + so no anti-RH antibodies will be produced

20
Q

If dad is Rh- and mom is Rh- is there a risk for an Rh factor during delivery

A

No the baby will have Rh - and neither the mom or baby will come in contact with Rh+ blood during delivery

21
Q

If father is Rh + and mother is Rh - is there a risk of Rh factor

A

Yes there is a 50% chance.
During pregnancy baby does not come in contact with moms blood.
During labor mom and baby blood mix and the Rh+ blood gets into mom’s Rh- blood - Mom’s blood now has Rh antibodies that attack rh+ blood cells
No problems caused until a 2nd pregnancy
If 2nd pregnancy moms blood passes through placenta causing Rh antibodies to attack Rh+ red blood cells

22
Q

What is the form of prevention for the Rh factor with pregnant woman

A

RhoGAM shot - given to RH- moms

blocks recognition of Rh +

23
Q

If a blood test is done on an unknown blood type and anti- A antibodies, Anti-B antibodies, and Anti-Rh antibodies are added to the blood type and clumpin happens in the Anti-A and the Anti-Rh what type of blood type is it

A

Blood Type A+

24
Q

What would happen in a blood test of an O- blood type

A

No clumping - mother would need RhoGAM

25
Q

What would occur in a blood test of AB+

A

Clumping of A, B, and Rh - Mother would not receive RhoGam because she is Rh +