LAB 2 Flashcards
Pupil also called
Apple of the eye
What type of reflex is blinking?
Somatic skeletal reflex
Hardest to override
The cornea is over the eye is the most sensitive area of the body
Corner of the eye, the little sphincter muscle does what
Sucts fluid across to the corner of the eye
Anterior cavity contains
Aqueous humor
Like water
The posterior cavity of the eye contains
Vitreous body
like jello
Keeps the retina in place
Macula lutea
Sharpest vision
Center of macula lutea
Fovea Centralis (Center of the retina, only contains cones)
Optic Disc
Blind spot - where optic nerve leaves retina, no photoreceptors present
Lens
Made of protein
Changes by ciliary muscle
Vascular tunic
Iris ciliary body and choroid
Fibrous tunic
Cornea and sclera
Sclera
White of the eye
Retina
Pigmented epithelial layer and neural layer (Photoreceptors), bipolar cells, ganglion cells (Axons form optic nerve)
Why are photoreceptors backwards?
Tips of photoreceptors burn out leaving garbage tissue, but macrophages can work behind the line of sight to clean up the dead tissue
Black pigment layer in people
Absorbs light so photoreceptors are only stimulated once
Iridescent layer in animal
Reflect photons of light that are absorbed, night vision but less clarity
Where do all senses go before consicous awareness?
Thalamus
Know the layers of the retina
Sclera, choroid, pigmented lauey, phtoreceptors …
Cones
Cones have higher visual acuity
Single bipolar cell and axon that connect to visual cortex
Require larger stimulus
Rods
Many rods are connected to single bipolar cell which travels to visual cortex
Less visual acuity
Rods use summation to reach the threshold
Vit A deficiency and afterimage
Rhodopsin falls apart when overstimulated, before it regenerates there is a negative afterimage (Lack of visual stimulus)
What shape is the lens for images farther away?
Flatter
Light is refracted by what
Cornea, lens, vitreous body
Lens is the only thing that can change
Why is looking at things up close harder
Ciliary Muscles are constantly contracted
Presbyopia
Cannot focus objects close to eye properly
Cannot round lens well anymore
Snellen eye chart
First number : Distance (Feet) Where you stand
Second number: Distance (Feet) Average person can see at
Why are more boys colourblind?
A recessive gene on the x chromosome
External Ear
Auricle, external auditory canal and tympanic membrane
The middle ear
Auditory ossicles (malleus, incus, and stapes), oval window, round window, and auditory tube
Internal ear
Vestibule, semicircular, canals and the cochlea
Function of earwax
Traps debris, regulates pH
Why is the low pH of ears good
Keeps bugs from making a home
Skin in the ear is replaced …
Sideways therefore skin cells are replaced sideways and debris moves out of your ear
Three smallest bones in body
Malleus, incus and stapes
How does thr tensor tympani muscle protect ear
Contracts and dampens the sound
Purpose of the middle ear
Allows for dampening of the sound
WHere is the equilibrim recepotrs of the ear
vestibule
Why rubbery end of oval window
Prevents reverberation and allows for distinct hearing
How do sound waves become nerve impulses
How many different semi circular canals
3
Where does the olfactory tract go
NOt to the thalamus - straight to the cortex
Hygiene in history
Could have prevented plagues
Fatality rate of having a baby in the possible
20% chance of death
The death rate of birthing after handwashing implemented
2%
Lining of the small intestine
Thousands of villi
Main function of digestive system
Nourishment for food
2 process of DS
Digestion and absorbtion
Digestion involves two things
MEchanical digestion and chemical digestion (Breakdown of molecular bonds)
Parts involved in DS
Mouth, esophagus, stomach,
Accessory parts that contribute from a distance to digestion
Liver pancreas salivary glands
4 layers of digestive tract (Vary in different parts epending on fucniton)
Mucosa: Epithelial tissue (Always present)
Submucosa: connective tissue (containing lots of glands to secrete enzymes for digestion and lubrication)
Muscularis: Longitudinal and circular layer smooth muscle layer
Serosa: Very thin layer that surround contours of digestive tract (Visceral layer of serous membrane)
Different parieta; peritoneal membranes
Mesentery: Coils the SO together and binds to the abdominal wall
Mesecolon: Binds I intestine to the posterior abdomen wall
Greater omentum: Fatty apron like fold hanging over intestine; adipose tissue and many lymph nodes
Lesser omentum: Connects stomach to liver
Falcifrom ligament: Connects the liver to the anterior abdominal wall
Digestion in the mouth
Salivary glands (exocrine glands which means they have ducts)
3 pairs of sa;ivary glands
Parotid, sublingual, and submandibular glands
Salivary gfland funciton
Moistens mouth and food
Contains enzymes such as :
amylase - breakdown of starch to sugar, pH of 7
Lingual lipase - activated at a low pH: in the stomach
The little flap that closes off the trachea
Epiglottis
4 layers of the esophagus
Mucosa: Stratified squamous epithelium
Submucosa (Very few glands)
Muscularais - 2 layers: Skeletal and smooth muscle
Adventitia - serosa: aelor CT and fibrous CT (
Peristalsis
Lower esoThe movement of smooth muscle
4 Areas of the stomach
Cardia: THe receivieing area
The fundus: The holding area
The body where all the action occurs
Pylorus: where food leaves the stomach
Rugae
Muscular folds of the stomach that allows the stomach to stretch
Extra layer in additino to 3 layers of smooth muscle in the stomach
Oblique layer: Mechanical digestion in the stomach
Pyrloric sphincter
Allowing chime to enter from the stomach into the small intestine
Goblet cells
Produce mucous that lubricate and in the stomach they release pepsinogen
Stomach pH level and reasons
Stomach produces HCL: pH 2-3
Acid kills most bacteria
Converts pepsinogen into pepsin which denatures proteins (unravels) does not chemically digest but makes it EASIER to digest
Purpose of mucous in the stomach
Protects the stomach from its own acid
Why does ther stomach release pepisnongen (Inactive pepsin)
Bc it would digest the stomach cells itself - the mucous layer protects against
Stomach ulcer
The wound in epithelial lining
How does stress contribute to stomach ulcers?
Reduces mucous production
What causes stomach ulcers?
H. Pylori, stress, alcohol, coffee
Parietal cells
Secrete HCl
Chief Cells
Columnar epithelial cells
3 Regions of the small intestine
Duodenum (10”s)
Jejunum (3’)
Ileum (6’)
Main site for digestion in small intestine
Duodenum
Funciton of the smal intestine
Complete digestion of all good tupes and absbtopm pf most nutrients
3 modifications of the small intestine
Histology of small intestine
Villi (Contains lacteal)
Intestinal glands: Secrete enzymes needed to complete digestion
Mucosa: Columnar epith. cell
Brush border enzymes
Absorptive cells - microbial
Goblet cells - secrete mucus
Enteroendocrine cells - secrete hormones
Is there a mucous layer in the small intestine?
No
What neutralizes the acid in the duodenum
Pancreas
What is the purpose of pressure receptors in pancreas?
As soon as you eat, the pancreas feels the pressure and then it will produce as much bicarbonate juice as the stomach produces HCl and then squirts the sodium bicarbonate into the small intestine (Exocrine portion_
How is the pancreas an endocrine gland
Insulin: Cells take up glucose
Glucagon:
Type 1 Diabetes
Autoimmune disorder: attacks the pancreas so it can no longer produce insulin
This means that they cannot digest sugar
Type 2 Diabetes
Cells have become desensitized to insulin
Caused by an unhealthy diet and not enough exercise (bc exercise stimulates sugar absorption, without exercise the body does not NEED to absorb sugar)
Pancreatic islet
The site of alpha and beta cells that produce insulin
WHy is pancertic cancer so dangereous
No serosa that surrounds the organ to contain it
Liver cells
Hepatocytes
What does the liver produce
Bile
What does bile do
Demlsifies the fat (Breaks up into smaller droplets) NOT chemical digestion, but mechanical
Where does bile flow
Through many ducts into the common bile duct
What does gallbladder do
Stores bile for the liver to digest fat
Additoinal function of bile
Detoxifies things, border patrol, anything passing from the liver is good for the body to use
Bile gets rid of the toxins and expells them through feces
Large intestine parts
Ascending, transverse, descending, and sigmoid colon, rectum, and anus
What does the large intestine function
More bacteria than cells in the organ (probiatics)
- They eat fiber
Byproducts - methane gas
Forms and solidifies feces
Which intestine absorbs more water
Small intestine
Most nutrients are absorbed
In the small intestine
What do the bacteria in the large intestine give us
Vitamin K: Crucial for blood clotting
Why should circumcision not happen immediately?
Bc the baby’s vitamin K is low bleeding and healing will not occur as well
There are more clotting agents in the human body on the 8th day than in any other day in one’s life
Appendix organ
A little safe house for bacteria
to repopulate the large intestine a lot faster if they are all washed out in sickness
Why is it important that feces are eliminated
Toxins from liver are stored in it
How does peristalsis increase
How is fiber “digested”
Drinking water
How are BMs promoted?
Exercise, drinking water
Why are Laxadives bad?
The large bowl becomes lazy and doesn’t stretch on its own
depends on laxatives
two sphincters of the anus
External and internal muscle sphicter
Large intestine has
Lots of goblet cells
What does bile do to fats?
Mechanically break them down into smaller pieces
What does chewing do
Promotes digestion, enhances flavour, enhances wellbeing
pepsin digestions
protein
lipase
digests fats
amylase digests
carbohydrates
What are enzymes
Proteins
What does an increase in temp in the body do to enzyme reactions
Inactivates reactions
That’s why high fevers are so dangerous
Enzyme reactions shut down
How many sources of lipase
3
Analyse
Intestinal secretions
pancreas
Function of SI
Digestion and absorption of most nutrients
What cells produce pepsin
chief cells
Kidneys located
Lower back, retroperitoneal
Only place structures leave the kidney
Hilum
Outer protection layer of kidney
Renal capsule
Why is fat tissue crucial for kdiney
Adipose capsule Keeps kidneys in place
Lower back pain in association with starvation
Depletion of fat tissue around kidneyA
Fat layer of kidney
Adipose capsule
Two kinds of nephrons
Cortical (Shorter and in cortex)
Juxtamedullary nephrn
Parts of nephron
Glomerular capusule
Glomerus part of nephron
NO, part of renal carpusle
Tubules function
To reabsorb nutrient
What is main function of loop of Henley
Water reabsor[tion
Brain and kidney
Take most of body energy
Why does medulla have high sodium content
So that water automatically osmosizes out of nephron into surrounding medulla tissue and will be reabsorbed passively
Glomerulus
The inner part of the renal corpuscel
Bowmans capsule
the balloon surrounding glomerulus
Endothelial membrane
Loosely fitting allowing for nonspecific filtration
Peritubular capilleries and vasa recta are essentially
Same thing but PC in cortex and VR in outer medulla
Secretion part of formation
Urea removed from blood and added to urine
Aldosterone
A hormone stimulating the reabsorption of Na in the distal convoluted tubule
What happens if sodium is reabsorbed
Water follows and moves into the bloodstream (decreasing amount of urine and increasing BP)
ADH
Anti-Diuretic Hormone
Anti-Diuretic Hormone function
Stimulates absorption of water into blood
3 Steps to form urine
Filtrations, reabsorption, and secretion (urea and waste products into the tubule out of bloodstream)
Cuboidal cells have what in the convoluted tubules
microvilli
Reabsorption in the tubules is what form
Active transport often
Mircorvilli helps because it provides more space for tunnels
Rough ER present in cuboidal cells
Produces protein for the protein trapsorters Active transport) Within tubules
Collecting duct drains into
capillary duct
Why are females more prone to UTIs
Females have shorter urethras (4cm) while males have a 20cm urethra
Sideaffects of urinary/bladder infections
Cognitive deficits
Transitional epithelium
A couple layers thick, the top cells can change shape (Flat to round)
Allowing the bladder to stretch
does diet affect urine
Yes
pH, gravity (Conc of solutes), and
Diabetes and glucose in the urine
Glucose blood levels do not lessen with insulin
Too much glucose in the bloodstream for active transporters to reabsorb back into bloodstream once it is filtered out and thus it stays in the urine
Which organs are part of endocrine system
Most
Main endocrine glands/organs
Thyroid, Pit gland, thymus, heart, stomach, kidney etc.
Endocrine
Release of hormone into bloodstream
Exocrine
Substance into duct (Only local)
Heterocrine
Both exo and endocrine funciton
Pit Gland
AKA hypophysis
Anterior: Adeno hypohysis
5 cells that produce 7 hormones
Posterior: neuro hypophysis
- Not cellular, releases only two hormones (does not produce them)
5 cells of the anterior pit gland
Somatothrophs - HGH: Growth hormone (specific function in puberty)
Lactotrophs - prolactin
Corticotrophs - andrenocorticotrophs
ACTH
MSH- Skin
Thyrotrophs - TSH
Gonadotrophs - FSH and LH
Know 5 cells and 7
Posterior pituitary
Looks more like Nervous system
Releases two hormones produced in the hypothalamus
Acts as storage for
Two cells that make up the post pit
- pituicytes
-Axon terminations of secretory cells (Nerosecretory cell)
Two hormones:
- ADH
- Oxytocin: Bonds mother and baby
- stimulates birth, produces milk in response to breast feeding
Hormone responsible for homesickness
Lack of oxytocin
Thyroid gland
located inferior to larynx
releases hormonese T3 and T4
- Regulate metabolism
3 and 4
- Regulated by iodine
colloid
Building blocks for thyroid hormone
Calcitonine
Takes calcium into bones
Parathyroid glands
4 pea-shaped glands
Chief cells
- produce Parathyroid hormone
: Takes calcium out of bones and puts it into bloodstream
Why must calcium levels be kept
For muscle contraction
Adrenal Gland
Located above the kidneys
Adrenal cortex
Secretes
1. mineralocoricorids- aldosterone
2. Glucocorticoids - cortisol
3. Androgens - secretes small amount of male sexhormnoes
Adrenal medulla
2 muscels of the testis
Dartos muscle and the cremaster muscle
Function of muscles in testis
To keep sperm at a term 3 degrees colder to mainain fertility
Cryptorchidism
Fetal development involving testes to fail to descend bw 7 months and birth
Why would laptop on lap increase infertility
Increasing temperature of sperm
How many lobules in testis divided into?
200-3000
Seminferous tubules
1-3 contained within each lobule of testis
Which cells produce testosterone
Structure of the sperm
Head containing nucleus and acrosome
Tail:
- Mitochondria
- Middle piece
- Principal piece
- End piece
What does acrosome contain
Enzymes to penetratrate the egg
Benefit of having the sperm swimming so far
Survival of the fittest
Abnormal sperm percentage in infertiility
1/3
Seminal vesicles
Squirt solution into ejaculatory duct
(semen)
- Alkaline (protecting against acidity of female reproductive system)
- Fructose (For energy)
- Prostoglandins (antiinflammatory to protct viability)
Contribute 60% of total semen volume
Prostrate gland
Size of golfball
Citric acid for ATP production
- 25% of semen volume
Prostate gland enlargement
Results in squished prostatic urethra
(longer for voiding)
Bulbourethral gland
Secrete alkaline fluid
- Secrete mucus for lubrication
Path of sperm
Seminiferous tubules
Straight tubules
Rete testis
Efferent ducts of epidymis
Ductus epididymis
Vas deferens
Ejactulatory duct
Prostatic urethra
Membranous urethra
Penile urethra
What is snipped in vasectomy
Vas deferens
What hold the female repro structures in place
ligaments
Cyclical avg.
28 days
Several hormones that are produced throughout female cycle
FSH (Follicle stimulating hormone)
Approx amount of eggs
400,000
FSH role
Primordial follicle
Primary follicle
Secondary Follicle
Graaffian follicle
Estrogen
Negative feedback to FSH (Strongest follicle survives)
Estrogen and Prostoglandin
Supress FSH (No new cycle starting randomly)
Build lining of uterus allowing embryo to implant itself
Corpus luteum
A clot around egg
Used to build up uterus in case of filtration
Disapears after cycle if not fertalized
3 Layers of uterus
Endometirum, myometrum, permetrium
Phases of female cycel
Menstrual phase
(lose lining of uterus)
Preovulatory phase
Ovulation
Postovulatory phase
Birth control
Progesteron and estrogen
Suppress levels of FSH produced
- Eggs deteriorate bc they rely on FS
IUD
Prevents implantation of embryo
Physical or hormonal
Endometriosis
When flow goes out into fallopian tubes and into the pelvic cavity endometrial tissue begins growing outside of uterus and can squish fallopian tubes
How can you tell if ovulation occured
Before ovulation it’s a low 36
after it’s a high 36
How many people with STDs are asymptomatic
70-80%
Fertilizaton nomrlaly occurs
At begining of FT
What are the two stages of the female cycel
ovarian and a uterine cycle.
Which layer of the uterus is shed during menstration?
stratum functionalis
Should the testis remain at body temp to promote fertility
NO
WHich cells guide in the process of spermato gneisis
Seratoli cells
Track flow of tears
Lacrimal Gland - Lacrimal duct - lacrimal canaliculi - lacrimal sac - nasolacrimal duct
Purpose of aqueos humor
Maintain intra ocular pressure
Glaucoma
Increased intraocular pressure from excessive aqueous humor - blindness
Two types of bipolar cells
Amacrine and horizontal
Layers of retina from deep to superficial
Superficial*
Sclera
Choroid
Pigmented layer
Photoreceptors
Bipolar cells
Ganglion cells
Optic nerve axons
DEEP*
Rod and cones differences
Rods - many more rods connect to single bipoar cell therefore increasing sensitivity to light but decreasing visual acuity
Cones are the opposite
Action of rhodopsin
Coloured photopigment that regenerates opsin in photreceptors after they have been stimualted, a lack in vit A would result in a longer after image
Parts of the external, middle, and internal ear
External
Auricle, ext. auditory canal, tympanic membrane
Middle
Ossicles (Malleus, incus, and stapes), oval window, round window, auditory tube
Internal
Vestibule, semicircular canals and cochlea
How does conduction in the ear occur
Air conduction to bone conduction to water conduction (to nerve conduction)
Two parts of inner ear
Cochlea and semicircual canals
Cochlea contains
Hearing recepotrs
Semicircular canal contains
Balance receptors
Pathway of auditory nerve impulse
Vestibulochochlear (VIII) - medulla - midbrain - thalamus - temporal lobe (auditory area) of cerebral cortex
Vestibule
Part of inner ear containing utricle and saccule which hold maculae, recepotrs for static equillibrium
which part of ear manages dynamic equillibrium
Semicircular canals
Earliest symptom of alzheimer’s disease
Lack of smell
Sclera venus sinus
Draining aqueous humour back into bloodstream
Fleshy part of theear frequently pierced?
Lobule
Rim of the auricle
helix
Study Pg. 382 and 383
Cochlea structure
Webber test, rinne testm barany test
Webber: Assesses for bilateral hearing loss
Rinne: Assesses for conduction deafness
Barany: Evaluates function of semicircular canals
Cribiform plate
Seperating nasal cavity and brain
Interconnected components of membranous labrynth
semicircular ducts
interconnected components of bony labyrinth
Semicircular canals
Crista
Detect rotational acceleration/decceleration
consit of har cells and supporting cells
What contains perilymph
Bony labyrinth
What contains endolymph
Within membranous labyrinth
How many semicircular canals
3
Semicircular ducts
secotions of mebrnaous labirinth connecting with utricle and containing equilibirum receptors
Ampulla of semicircular canal/duct
Widened end of each
Cochlea
Spiral end of bony labryth
Cochear duct,
section of membranous labith within cochlea containing hearing receptors and connected to saccule
Track flow of kidney blood supply
Renal artery - Interlobular arteries - arcuate arteries - radiate arteries - venae rectae