l9 Flashcards
key genetic factors are
circumventing plelotropy
event frequency
plelotropy is what
when 1 change has multiple consequences
gene duplication and divergence minimizes _____, but is an infrequent event
pleiotropy
protein sequence evolution is frequent, but ______
pleiotropic
cis-regulatory sequence evolution can change with mutation in one single ____, and minimizes _____ and is frequent
base
pleiotropy
what is an example of cis-regulatory evolution of a hox gene in drosophila?
closely related flies have differences in trichomes on the T2 leg
evolution of trichome patterns are a result of changes in _____ expression cis-regulatory sequences
Ubx
Ubx protein = identical and not functional change in protein so the only thing that can be changed is expression
DNA footprinting is a powerful technique for identifying __________ interactions.
protein-DNA
_______are a useful group to study the evolution of morphological diversity in limb number and structure
arthropods
_______ promotes limbs in fly embryos, _____ and _______ hox proteins repress limbs
distalless
Ubx
AbdA
______ ubx represses larval limbs, but _____ ubx does not
drosophila
artemia
artemia ubx is a functional repressor of some genes in drosophila, but not of limb-promoting genes like ____
distalless
differences in _________ residues between fly and custacean ubx control whether limbs are repressed
c-terminal
the c-terminus of artemia ubx inhibitss a ________ limb repression function, and the c-terminus of drosophila ubx is _______ for limb repression
covert
permissive
varation in the number of ______ residues may account for subtle morphological differences even within a species
Ser/Thr
