L7. Inhalation Anesthetics

Question 1

Halothane

Answer 1

Highly potent
Inhalation anesthetic

SE: hepatitis, malignant hyperthermia

Question 2

-flurane

Answer 2

Inhalation anesthetics

Question 3

Enflurane

Answer 3

Inhalation anesthetic

Not safe

Question 4

Isoflurane

Answer 4

Inhalation anesthetic

Expensive

Question 5

Desflurane

Answer 5

Inhalation anesthetic

Rapid elimination

Question 6

Nitrous oxide

Answer 6

Inhalation anesthetic
NMDA antagonist
Sympathomimetic

SE: dec Vit B12 and B12 dependant enzymes
Megaloblastic and hyperchromic

“ big black red blood cells”

Myelin production also affected

Question 7

Ether issue?

Answer 7

Only flammable
inhalation anesthetic

Too much = resp depression
Too little = pain remains

Highest B/G sol
= very slow

Question 8

What can you give through tube?

Answer 8

Lidocaine, epinephrine, atropine, furosemide, opioids

Question 9

What can’t you give through tube?

Answer 9

Acidic drugs/ bicarb

Question 10

Blood gas sol effects on inhalation anesthetics

Low?

High?

Answer 10

Low: QIQO

High: SISO

Question 11

Current view of MOA of inhalation anesthetics?

Answer 11

Have agonist effect on GABA

Question 12

Vasopharyngeal detection devices?

Answer 12

Use when you can’t use capnometer (in resuscitation conditions)

To check whether tube went into lungs or not

Question 13

Highest B/G?

Answer 13

Ether = very slow

Question 14

Highest MAC?

Answer 14

Nitrous oxide

= ineffective by itself, used in combination