L6. Non Depolarizing Muscle Relaxants Flashcards
Pipecuronium
Amino steroids
VL
H/R/B
5/4
Pancuronium
Amino steroid
L
1st drug, inc tachycardia
H/R/B
3/6
Vecuronium
Amino steroid
I
H/R/B
3/2/3
Rocuronium
Aminosteroid
I
H/R/B
0/Y/Y
Mivacurium
Isoquinolones
Short acting
Cisatracurium
Isoquinolones
Laudonosine
Intermediate
Doxacurium
Isoquinolone
Very long
Sugammadex
Aminosteroid binding agent
NDMR action
Stop Na channel from opening
Isoquinolones vs amino steroids
Location?
Iso - south america
Amino - africa
Isoquinolones special action?
Associated with more histamine release than curoniums (amino steroids)
Effects:
Tachycardia
Vasodilation
Dec BP
NMDR + meds?
Sedative hypnotic, analgesic, intubation (ventilated), and
Stigmine + atropine
NMDR + stigmine + med?
Why?
Med = atropine
To treat bradycardia associated with stigmines
NMDR TOF?
Fade!
II Ii