Krebs Cycle Flashcards
where does glycolysis occur
the cytoplasm
where does krebs cycle occur
in the matrix
describe pyruvate oxidation/oxidative decarboxylation
pyruvate (3C) is converted into acetyl-CoA (2C) in order to be brought into the mitrochondria
what reaction types happen is pruvate oxidation/pxidative decarboxylation
- decarboxylation
- redox
- synthesis
what enzymes are working during pyruvate oxidation/oxidative decarboxylation
- decarboxylase
- dehydrogenase
- synthase
what happens to energy during pyruvate oxidation/oxidative decarboxylation
energy is released - produces energy
describe coenzyme A
a large organic molecule with the active functional group thiol - AKA CoA-SH
What is inputted + produced/ released in pyruvate oxidation + quantities
2 pyruvate becomes 2 acetyl-CoA 2 CO2 are also released and 2 NADH is produced
net changes for each turn of the Krebs cycle
- two carbons exit completely as CO2
- three NADH formed
- one FADH2 formed
- one ATP made by substrate level phosphorylation
describe step one of the Krebs cycle + reaction type + enzyme + energy change
joins a 2 carbon molecule with a 4 barcon molecule and recycles CoA
reaction type: synthesis
enzyme: synthase
energy is absorbed
describe step 2 of the Krebs cycle + reaction type + enzyme + energy change
rearrangement of atoms with the help of H2O
reaction type: isomerazation
enzyme: isomerase
no energy change - equilibrium
describe step 3 of the Krebs cycle + reaction type + enzyme + energy change
synthesis of CO2 and NADH the 6 carbon molecule becomes a 5 carbon molecule
reaction type: decarboxylation, redox
enzyme: decarboxylase, dehydrogenase
energy is released
describe step 4 of the Krebs cycle + reaction type + enzyme + energy change
synthesis of CO2 and NADH the 5 carbon molecule becomes a 4 carbon molecule and CoA comes back
reaction type: decarboxylation, redox, synthesis
enzyme: decarboxylase, dehydrogenase, synthase
energy is released
describe step 5 of the Krebs cycle + reaction type + enzyme + energy change
ADP phosphorylation to ATP, CoA is recycle
reaction type: substrate-level phosphorylation, cleavage
enzyme: kinase, lyase
energy is released
describe step 6 of the Krebs cycle + reaction type + enzyme + energy change
FADHs formed
reaction type: redox
enzyme: dehydrogenase
energy is released
