Kin 131 exam integumentary system Flashcards

1
Q

What does the integumentary system include?

A
  • Skin
  • assessor structures
  • Hair, nails, glands
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2
Q

What are the 7 primary functions of the integumentary system?

A
  1. protection
    - UV protection (melanin)
    - Physical trauma protection
    - Protection against fluid loss
  2. Excretion
    - Gets rid of waste via sweat
  3. Lubrication
    - sebaceous glands produce oil
  4. Body temperature
    - Vasoconstriction = reduce temperature in target area
    - Vasodilation = increase temperature in target areas
  5. Vitamin D synthesis
    - Produces vitamin D which produces a hormone called calcytrial that facilitates absorption of calcium
  6. Lipid storage
    - Helps insulate body and provide energy
  7. Sensations
    - contains receptors that help us understand the world around us
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3
Q

Explain the anatomy of the cutaneous layer and the subcutaneous layer

A
  1. Cutaneous layer:
    - Epidermis
    - Dermis
  2. Subcutaneous layer
    - Hypodermis (provides support functions)
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4
Q

Explain the cutaneous and subcutaneous layers of the skin in depth

A
  1. Epidermis:
    - The outermost layer of the skin.
    - Made up of 4-5 layers of tightly packed stratified squamous epithelial cells (flat cells stacked on top of each other).
    - The epidermis acts as a barrier to protect the body from the environment.
  2. Dermis:
    - The inner layer of the skin, beneath the epidermis.
    - Made up of 2 layers
    - The dermis contains blood vessels, lymphatic vessels, glands, nerves, and hair follicles. It supports and nourishes the epidermis.
  3. Hypodermis (Subcutaneous Layer):
    - Located beneath the dermis.
    - Highly vascularized (rich in blood vessels).
    - The hypodermis connects the skin to the underlying fascia
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5
Q

What is the epidermis primary made of? What does it do?

A

keratinocytes, which primary provide hardness and water resistance

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6
Q

How many layers are in the epidermis?

A

Either 4 or 5
- 5 layers in thick skin: Palms and soles of feet
- 4 layers in thin skin: rest of body

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7
Q

Explain the different layers of the epidermis

A
  1. Stratum basale (stratum germanium):
    - Deepest layer
    - Single layer of basal cells (turn into keratinocytes)
    - Attaches epidermis to the dermis *
  2. Stratum spinosum:
    - 2nd deepest layer
    - 8-10 layers of keratinocytes
    - Keratonocytes begin to synthesize keratin
    - Contains langerhans that act as macrophages, cleaning up unwanted substances
  3. Stratum granulosum:
    - 3rd deepest layer
    - grainy appearance
    - 3-5 layers of keratonocytes
    - produces the largest amount of keratin
    - produces keratohylin (protein that helps with waterproofing)
    - Cells become flatter and begin to die
  4. Stratum lucidum:
    - Only in thick skin
    - Cells are flattened and dead
    - contains eledein (increases waterproofing and physical strength)
  5. Stratum corner
    - Outtermost layer
    - 15-30 layers of keratonocytes
    - layers of dead cells
    - entire layers if replaced every 4 weeks ish
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8
Q

What are basal cells

A

cuboidal shape stem cells that turn into keratinocytes

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9
Q

What is keratin?

A

A protein known for being tough and water resistant (called a scleroprotein)

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10
Q

Explain what can effect the colour of skin

A
  1. Melanin:
    - Produced by melanocytes
    - packaged into melanasomes
    - further the melanosomes travel into the epidermis layers before being broken down and the larger they are = darker skin
    - Melanin protects skin from UV damage
    Melanin production is stimulated by UV exposure
  2. Carotene
    - Causes a yellow/orange pigment
  3. Circulation and temperature
    - Oxyhemoglobin (oxygenated blood) = red colour
    - Cyanosis: caused by deoxygenated blood = blue colour
    - Cold = vasoconstriction = blue
    - Hot =. vasodilation = red
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11
Q

What does having too much melanin do?

A

Can affect synthesis of vitamin D as it blocks too much UV light

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12
Q

Explain the dermis and its layers

A
  • Found beneath the epidermis layers
  • Made of collagen and elastin fibres which give the skin strength and flexibility
  • Has 2 layers:
  1. Papillary layer:
    - Superficial layer
    - Has dermal papilla which are bumps that form fingerprints and are used to lock the dermis to the epidermis
  2. Reticular layer
    - Deeper layer
    - Dense irregular tissue
    - Contains hair follicles, sweat and oil glands
    - stronger and less flexible than papillary layer
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13
Q

Explain what lines of cleavage are

A
  • The orientation of the underlying collagen fibers in the body
  • Provides better resistance to certain forces
  • In surgery, cuts are made with the lines of cleavage as it reduces scaring
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14
Q

Explain the integumentary system accessory structure: Hair

A
  • Made of dead keratinocytes
  • Hair grows from a structure called the hair follicle, which is a tiny pocket in the skin.
  • The hair follicle is an extension of the epidermis (the outer skin layer) that dips into the dermis (the deeper skin layer).
  • Inside the hair follicle, there are several important parts (Hair root: beneath the skin):
    1. Hair bulb: Structure at the base of the hair
    2. Hair matrix: The part of the bulb where cells rapidly divide and produce new hair.
    3. Hair papilla: A structure at the base of the bulb that contains blood vessels, which nourish the growing hair.
  • (Hair shaft: above the skin): Part of the hair that’s above the skin
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15
Q

What are the layers of the hair?

A
  1. Medulla: Core part of the hair
  2. Cortex: Layer pf compressed keratinized cells that’s around the medulla
  3. Cuticle Hard keratinized cells that form outside of hair
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16
Q

What are the main functions of hair?

A
  1. Protection
    - protection from sun
  2. Sensory info
    - Root hair plexus
  3. Thermoregulation
    protection from heat and cold

4.comunication
- With sympathetic activation the hairs stand up

17
Q

Explain the stages of hair growth

A
  1. Anlagen stage:
    - Lasts 2-7 years
    - Cells dividing rapidly and pushing the hair out of the follicle
  2. Catogen stage
    - Lasts 2-3 weeks
    - Transition from growth to rest
    - Slowed growth
  3. Telogen stage
    - Lasts 2-4 months
    - No new growth
    - Old hair shed and cycle repeats
18
Q

What’s is hair growth affected by:

A

Age, Hormones, Stress, Meds

19
Q

Explain the main function and types of sweat glands

A
  • Eliminate waste and regulate temp through sweat

2 main types:

  1. Eccrine:
    - Coiled structure
    - Secrete sweat directly onto the skin
    - Secretion is watery and clear
    - main function is thermoregulation
  2. Apocrine
    - Secrete sweat into hair follicles
    - Secretion is thicker and cloudier acting as nutrient for bacteria living on the skin
    - secretion due to stress or puberty
20
Q

explain oil glands and their function

A
  • Sebaceous glands secrete a oily substance called sebum into hair follicles

Functions:
- Provides lubrication to the epidermis to keep it soft and flexible
- Helps clean the skin
- helps with waterproofing

21
Q

Explain nails and their structure

A
  • hard structure at the ends of digits made of dead keratinocytes

Structure:
- Nail body: hidden base part of the nail under the cuticle

  • Nail matrix: Area where the basal cells produce new cells that turn to keratinocytes
  • Nail body: Nail itself
  • Lunula: White half moon structure at the base of the nail
  • Cuticle: dead layers of cells that sit overtop the nail root
  • Proximal and lateral nail folds: sides of the nails
  • Nail bed: Skin underneath the nail body
  • hyponychium: dead skin underneath the nail free edge
22
Q

How fast is the nail growing? What’s it a good indicator of

A

Matrix produces new cells at a rate growing the nail 3mm a month. good indicator of mineral deficiency if bumps on nail

23
Q

How age affects the integumentary system

A
  1. fewer melanocytes
    - become paler
  2. Decrease in germinative cell division
    - Thinner epidermis
    - lose ability so synthesize vitamin D
  3. Fewer elastin fibers
    - Saggy skin
  4. Eccrine sweat glands are less active
    - less effective at regulating temp
  5. Less active hair follicles
    - less hair
  6. reduced sebaceous gland activity
    - dryer skin
  7. reduced sex hormones
24
Q

what is albinisme and vitiligo?

A

A disorder resulting in the absence of melanocytes

  • in albinisme it affects the eyes skin and hair
  • In vitiligo its only affects some areas of the skin

neither have a direct impact on lifespan but indirect factors caused by them do affect lifespan

25
Q

What is skin cancer?

A

-Abnormal uncontrollable growth of cells

-When theirs a flip a switch often caused by radiation that causes a cell to divide rapidly without dying, causing a large buildup of cells. This steals nutrient away from the rest of the body

26
Q

What is carcinoma and what are the different types?

A
  • cancer in the epithelial cells of the skin
  1. Basal cell carcinoma
    - Most common
    - Doesn’t tend to spread
    - Buildup of cells in the stratum germinative
  2. Squamous cell carcinoma
    - Buildup of cells in the stratum spinuosum
    - Non life threatening unless untreated
  3. Melanoma
    - Lest common and most dangerous
27
Q

How are moles assessed?

A

Asymmetrical
Boarders
- fuzzy borders = bad
Colour
- white or abnormal colour = bad
Diameter
- over 6mm = bad
Evolving
-changing over time

28
Q

how are moles treated?

A
  1. Remove mole and tissue around it
  2. If all cancer is removed then stop
  3. If cancer is still present new treatment such as chemotherapy begins
29
Q

What are the different types of burns

A
  1. First degree
    - Burn to the epidermis
  2. Second degree
    - burn to the dermis
  3. Third degree
    - Burn to the hypodermic
    not painful
  4. Fourth degree
    - burn to the facia or bone
30
Q

What are the types of wound healing

A
  1. Primary intention
    - wound edges are brought together
  2. Secondary intention
    - wound edges are too far apart so wound heals from bottom up
  3. Tertiary intention
    - Mix of the first two, wound is left to close then brought together
31
Q

W\Explain the wound healing stages

A
  1. Hemostasis
    - Clot formation
    - vasoconstriction
  2. Inflammatory
    - Vasodilation occurs bringing immune cells
  3. Proliferative
    - New cells are built to repair damage
  4. Remodelling / maturing
    - Collagen strengthens and reorganizes itself
32
Q

what is a scar and What are the types of scars?

A

Scar: High density of collagen fibers

Atrophic scar:
- Has a indented structure
- Less collagen fibers than other scars

Hypertrophic scar
- Bubbles out structure but stays within injury area
- Has more collagen then normal scars

Keloid scar:
- Extreme amounts of collagen
- Scar bubbles out and expand outside of the injury area