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MRCP Endocrine & Diabetes > Kallman's > Flashcards

Kallman's Flashcards

1
Q

How is Kallman’s inherited?

A

X-linked recessive trait.

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2
Q

Pathophysiology of Kallmans

A

failure of GnRH-secreting neurons to migrate to the hypothalamus.

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3
Q

Clinical features of Kallman’s

A

‘delayed puberty’
cryptorchidism
ANOSMIA
sex hormone levels are low
typically normal/above-average height

Some Cleft lip/palate and visual/hearing defects

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4
Q

Management of Kallman’s

A
  • testosterone supplementation
  • gonadotrophin supplementation
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MRCP Endocrine & Diabetes (54 decks)

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