Gynaecomastia

Question 1

What hormone imbalance causes gynaecomastia

Answer 1

increased oestrogen:androgen ratio

Question 2

Causes of gynaecomastia

Answer 2

androgen deficiency: Kallman’s, Klinefelter’s
testicular failure: e.g. mumps
liver disease
testicular cancer
ectopic tumour secretion
hyperthyroidism
haemodialysis

Question 3

Drugs causing gynaecomastia

Answer 3

spironolactone
cimetidine
digoxin
cannabis
finasteride
GnRH agonists e.g. goserelin, buserelin
oestrogens
anabolic steroids

Question 4

Rare drug causes of gynaecomastia

Answer 4

Tricyclics
isoniazid
calcium channel blockers
heroin
methyldopa