Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Endocrinology Fellowship > Journals And Endocrine News > Flashcards

Journals And Endocrine News Flashcards

0
Q

What could low kisspeptin levels in early pregnancy predict?

A

Miscarriages

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
1
Q

What happens to insulin sensitivity in growth hormone receptor deficiency?

A

Increased insulin sensitivity that protects against diabetes and deceases cancer risks.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is IDegLira?

A

Combination of degludec and liraglutide.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Does intensive glucose control after coronary bypass grafting reduce complications?

A

No.

Targets of 100 - 140 mg/dL were no better than targets of 140 - 180 mg/dL.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What kind of drug is Belviq (lorcaserin)?

A

Weight loss drug.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is the mechanism of action of lenvatinib?

A

Multi-tyrosine kinase inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Non-alcoholic fatty liver disease is strongly linked to increased incidence of chronic kidney disease.

True or false?

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

How many families of thyroid hormone receptors are there, through which thyroid hormone function is meditated?

A

2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Which one is the prohormone -

T3 or T4?

A

T4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Does tight blood glucose control slow down the progression of diabetic neuropathy?

A

In type 1 diabetes but not type 2 diabetes.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Name two studies that show that tight glycemic control in type 1 diabetes may limit the progression of diabetic neuropathy?

A

DCCT

EDIC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Name four studies/trials that show tight glycemic control does not affect neuropathy in type 2 diabetes.

A

UKPDS
ACCORD
VADT
ADVANCE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Which thyroid hormone receptor is a non-hormone-binding variant protein?

A

(TR) alpha 2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Which gene is affected in thyroid hormone resistance syndrome?

A

Thyroid hormone receptor alpha gene

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Familial hyperchylomicronemia.

Frederickson hyperlipoproteinemia phenotype?

A

Type 1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Familial hypercholesterolemia.

Fredrickson hyperlipoproteinemia phenotype?

A

Type 2A

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Combined hyperlipoproteinemia.

Frederickson hyperlipoproteinemia phenotype?

A

Type 2B

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Dysbetalipoproteinemia.

Fredrickson hyperlipoprotemia phenotype?

A

Type 3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Primary or simple hypertriglyceridemia.

Fredrickson hyperlipoprotemia phenotype?

A

Type 4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Mixed hypertriglyceridemia.

Fredrickson hyperlipoprotemia phenotype?

A

Type 5

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What is the main lipid change in type 1 hyperlipoprotemia?

A

Increased triglycerides.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

What is the main lipid change in type 2B hyperlipoprotemia?

A

Increased total cholesterol.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

What is the main lipid change in type 2B hyperlipoprotemia?

A

Increased total cholesterol and increased triglycerides.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

What is the main lipid change in type 3 hyperlipoprotemia?

A

Increased total cholesterol and increased triglycerides.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

What is the main lipid change in type 4 hyperlipoprotemia?

A

Increased triglycerides.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

What is the main lipid change in type 5 hyperlipoprotemia?

A

Increased total cholesterol and increased triglycerides.

26
Q

What is the primary lipoprotein change in type 1 hyperlipoprotemia?

A

Increased chylomicrons.

27
Q

What is the primary lipoprotein change in type 2A hyperlipoprotemia?

A

Increased LDL

28
Q

What is the primary lipoprotein change in type 2B hyperlipoprotemia?

A

Increased VLDL and increased LDL.

29
Q

What is the primary lipoprotein change in type 3 hyperlipoprotemia?

A

Increased IDL

30
Q

What is the primary lipoprotein change in type 4 hyperlipoprotemia?

A

Increased VLDL.

31
Q

What is the primary lipoprotein change in type 5 hyperlipoprotemia?

A

Increased VLDL and increased chylomicrons.

32
Q

What do LDL receptors in the liver do?

A

Remove LDL Cholesterol from circulation.

33
Q

What does PCSK9 do to LDL receptors?

A

Binds to them promoting their degradation.

34
Q

What does PCSK9 do to the LDL cholesterol levels?

A

Increases them

35
Q

PCOS involves a degree of low level inflammation.

True or false?

A

True

36
Q

Is pregnancy a low level inflammation state?

A

Yes

37
Q

Should you hold back when treating thyroid storm?

A

No - hit it with everything you have.

38
Q

Is the prevalence of congestive heart failure in type 2 diabetes mellitus more than that of the general population?

A

Yes

39
Q

The risk of cardiovascular disease is increased by ____ times in patients with type 1 diabetes mellitus.

A

10

40
Q

Levonorgestrel 1.5 mg (emergency contraception pill) loses it potency in women over what weight?

A

165 lbs

41
Q

Levonorgestrel 1.5 mg (emergency contraceptive pill) does not work in women above what weight?

A

175 lbs

42
Q

Decreased efficacy of levonorgestrel 1.5 mg (Plan B) is seen above what BMI?

A

25

43
Q

Levonorgestrel 1.5 mg (Plan B) stops working entirely in women over what BMI?

A

30

44
Q

What is ulipristal acetate (Ella) used for for?

A

Emergency contraception

45
Q

What is the onset of action of U-500?

A

30 - 45 minutes

46
Q

Metformin is contra-indicated equal to or above creatinine ______ in males.

A

1.5 mg/dL

47
Q

Metformin is contra-indicated with creatinine equal to and above ______ in females.

A

1.4 mg/dL

48
Q

Metformin is contraindicated in GFR less than ______.

A

45 mL/min/1.73m2

49
Q

Does cardiovascular risk correlate more with LDL cholesterol or LDL particle number?

A

LDL particle number

50
Q

Does metformin control blood glucose better in Black patients or White patients?

A

Black patients.

51
Q

Should the steroids be given before or after radioactive iodine ablation in patients with Graves Ophthalmopathy?

A

After.

52
Q

Which is the most common site of bone metastases due to thyroid cancer?

A

Spine

53
Q

Which is the dominant enzyme driving conversion from T4 to T3?

A

Deiodinase type 1

54
Q

What happens to deiodinase type 1 during fasting?

A

It is suppressed.

55
Q

What happens to T3 levels during fasting?

A

They decrease.

56
Q

What happens to the activity of deiodinase type 3 during fasting?

A

It is increased.

57
Q

Have randomized controlled trials shown benefit on patient outcomes of treating ‘euthyroid sick syndrome’ or ‘non-thyroidal illness in the ICU’ with therapeutic doses of T3 or T4?

A

No

58
Q

What happens to the plasma T3 levels in times of acute stress (acute illness, surgery, severe physical stress)?

A

T3 levels acutely fall.

59
Q

TSH has a normal nocturnal surge.

True or false?

A

True

60
Q

What happens to the normal nocturnal TSH surge in acute illness?

A

It is absent.

61
Q

Vandetanib can prolong QT interval.

True or false?

A

True

62
Q

High serum TSH levels are associated with retinal arteriolar narrowing.

True or false?

A

True.

Endocrinology Fellowship (30 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions