Fellowship - March 2015

Question 0

Van Wyk Grumbach syndrome - what is the triad?

Answer 0

• Primary hypothyroidism
• Precocious puberty
• Polycystic ovaries (on imaging)

Question 1

Is the increased cortisol during an acute illness a production issue or a metabolism issue?

Answer 1

It is because of decreased metabolism of cortisol during acute illness.

Question 2

What endocrine problem does ipilimumab cause?

Answer 2

Hypophysitis or hypopituitarism

Question 3

When is metformin used in pregnancy?

Answer 3

When patient has polycystic ovarian syndrome

Question 4

What’s the strongest correlation for percentage body fat of infant?

Answer 4

Maternal triglyceride levels

Question 5

What will the ratio of inferior petrosal sinus ACTH be to peripheral ACTH in the case of a pituitary ACTH source?

• without CRH
• with CRH

Answer 5

Without CRH: more than 2

With CRH: more than 3

Question 6

What FDA pregnancy class is gemfibrozil?

Answer 6

C

Question 7

How is extreme hypertriglyceridemia in pregnant women usually managed?

Answer 7

• Extremely low fat diet

- Fish oil therapy

Question 8

What should the adrenal vein cortisol to inferior vena cava cortisol ratio be when cosyntropin is infused?

Answer 8

More than 5:1

Question 9

What should the ratio of cortisol corrected aldosterone be from high to low side if there is aldosterone excess?

Answer 9

More than 4:1

Question 10

What is important when measuring chromogranin A levels?

Answer 10

That they be fasting