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Endocrinology Fellowship > Fellowship - November 2014 > Flashcards

Fellowship - November 2014 Flashcards

0
Q

Does metreleptin help with weight gain (when treating lipodystrophy)?

A

No - it does not help weight gain.

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1
Q

Why is mifepristone only FDA approved in diabetic or glucose intolerant patients?

A

Because glucose is the only reliable way of monitoring therapy.

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2
Q

What is the size of macroprolactin?

A

150 kDa

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3
Q

What is the size of Big prolactin?

A

50 kDa

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4
Q

What is the size of monomeric prolactin?

A

23 kDa

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5
Q

Is the biological activity of macroprolactin lower or higher than prolactin?

A

Lower

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6
Q

Does macroprolactinemia cause symptoms?

A

No

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7
Q

If a patient has galactorrhea or oligomenorrhea and has macroprolactinemia… Is the macroprolactinemia the cause?

A

No.

No data show the symptoms are related.

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8
Q

What symptom is low prolactin levels associated with?

A

Low libido

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9
Q

What does leptin do to appetite?

A

Suppresses it.

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10
Q

Does mifepristone cause hypo- or hyperkalemia?

A

Hypokalemia

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11
Q

On average how much glucose is filtered by the kidneys per day?

A

180 grams

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12
Q

Survival of patients with BRAF mutation is lower than those without.

True or false?

A

True

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13
Q

Can radioactive iodine treatment for Grave’s disease cause thyroiditis?

A

Yes

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14
Q

How is radioactive iodine induced thyroiditis treated?

A

NSAIDS

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15
Q

Baxerotene can cause low HDL that recovers when patient stops the medication.

True or false?

A

True

16
Q

Do the pituitary and stalk have a blood brain barrier?

A

No

17
Q

RANKL is on lymphocytes.

True or false?

A

True

18
Q

What is the biggest trial with denosumab?

A

FREEDOM trial.

19
Q

Which adrenal vein is harder to cannulate?

A

Right adrenal vein

20
Q

If the Afirma is positive then what’s the chance of malignancy?

A

Approximately 40%

21
Q

Vandetanib is approved for symptomatic or progressive medullary thyroid cancer in patients with unresectable locally advanced or metastatic disease.

True or false?

A

True

Endocrinology Fellowship (30 decks)

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