Fellowship - October 2014

Question 0

What do steroids do to ADH?

Answer 0

Suppress it.

Question 1

Which SSRI is FDA approved for hot flashes?

Answer 1

Paroxetine

Question 2

What is the most common cause of uric acid stones?

Answer 2

Low pH

Question 3

Does toxic multinodular goiter ever burn out?

Answer 3

No

Question 4

Which two places does follicular carcinoma of the thyroid typically metastasize to?

Answer 4

• Lung

- Bone

Question 5

All patients with follicular carcinoma of the thyroid get radioactive iodine remnant ablation.

True or false?

Answer 5

True

Question 6

All the criteria of SIADH are met; but the ADH levels are undetectable.

Diagnosis?

Answer 6

Nephrogenic syndrome of inappropriate antidiuresis.

Question 7

What causes nephrogenic syndrome of inappropriate antidiuresis?

Answer 7

Gain-of-function mutation in the renal vasopressin V2 receptor causing increased water resorption.

Question 8

Per the GEMINI trial which causes more increased insulin sensitivity; metoprolol or carvedilol?

Answer 8

Carvedilol because of its alpha-blocking activity.

Question 9

What happens to bone mineral density in the first year after solid organ transplantation (e.g. heart transplant)?

Answer 9

Decreases (large and rapid decline).

Question 10

Where in the sleep cycle is the cortisol level the highest?

Answer 10

Immediately after waking up (8 am).

Question 11

What does heparin do to free T4 levels?

Answer 11

Increases them.

Question 12

Woman with short stature (compared to parents) presents with hyperandrogenism, oligomenorrhea and infertility.

Diagnosis?

Answer 12

Non-classical congenital adrenal hyperplasia.

Question 13

How many surgical levels of the neck are they?

Answer 13

6

Question 14

Amiodarone induced thyrotoxicosis type 1.

Etiology?

Answer 14

Underlying thyroid disease.

Question 15

Amiodarone induced thyrotoxicosis type 1.

Treatment?

Answer 15

Anti-thyroid medications.

Question 16

Amiodarone induced thyrotoxicosis type 2.

Etiology?

Answer 16

Destructive thyroiditis (direct toxicity of amiodarone).

Question 17

Amiodarone induced thyrotoxicosis type 2.

Treatment?

Answer 17

Glucocorticoids (prednisone 40 - 60 mg daily tapered over 2 - 3 months.

Question 18

Are uric acid stones radio-opaque or radiolucent?

Answer 18

Radiolucent

Question 19

What are the three main (naturally occurring) food sources of vitamin D?

Answer 19

• Fish
• Egg yolk
• Mushrooms

Question 20

Why do you need to order CT of the adrenals even if primary hyperaldosteronism has been biochemically confirmed instead of just proceeding with AVS?

Answer 20

To rule out adrenal carcinoma.

Question 21

What is the pleural of xanthelasma?

Answer 21

Xathelasmata

Question 22

Xanthoma

Answer 22

Xanthomata

Question 23

Is Cushing’s syndrome caused by excess cortisol secretion from adrenal nodules more common in males or females?

Answer 23

Equally common in both.

Question 24

Is Cushing's disease (pituitary source) more common in males or females?

Answer 24

Females

Question 25

If the ACTH is less than 10 and cortisol is high then what is the source of the excess cortisol?

Answer 25

Adrenal gland

Question 26

If the ACTH is more than 25 and the patient has cortisol excess, what's the diagnosis?

Answer 26

Cushing's disease

Question 27

What does the cortisol have to be for the metyrapone test to be adequate?

Answer 27

Less than 5 mg/dL

Question 28

In primary biliary cirrhosis is LDL cholesterol rich or triglyceride rich?

Answer 28

Triglyceride rich.

Question 29

In primary biliary cirrhosis is VLDL more cholesterol rich or triglyceride rich?

Answer 29

Cholesterol rich.

Question 30

What kind of glucose is the purple PD bag?

Answer 30

Icodextrin

Question 31

How often do you give denosumab in bony metastasis secondary to prostate cancer?

Answer 31

Every 28 days.

Question 32

If patient has hypoglycemia and they are on beta-blockers (non-selective) then which clinical response will still occur?

Answer 32

Sweating

Question 33

Which short acting insulin analog can you not use T-slim pumps?

Answer 33

Apidra

Question 34

Does the glucose correct to the lower number or the higher number of the glucose target when using an omnipod?

Answer 34

Lower number

Question 35

What is the inheritance pattern of Pendred Syndrome?

Answer 35

Autosomal recessive.