Irritable Bowel Syndrome Flashcards

1
Q

What hormones are involved in perception of autonomic response to visceral stimulation?

A

Serotonin
Substance P
Norepinephrine
Nitric Oxide

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2
Q

What is Irritable bowel syndrome (IBS)?

A

Chronic disease (>3months) characterized by abdominal pain or discomfort that occurs in association with altered bowel habits

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3
Q

What is believed to play a large role in IBS?

A

Mental health

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4
Q

What age does IBS normally begin?

A

Late teens to early twenties

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5
Q

Hallmark sx of IBS?

A

Abdominal discomfort relieved after defecation

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6
Q

What kind of abdominal pain do patients with IBS have?

A

Intermittent, crampy in lower abdominal region

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7
Q

Dx of IBS is based on what 2 out of 3 features?

A

Relieved with defecation
Onsite associated with a change in frequency of stool
Onsite associated with a change in form of stool

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8
Q

What 3 categories are patients with IBS classified?

A

IBS with constipation (IBS-C) or/with diarrhea (IBS-D)
Infrequent bowel movements (IBS-U)
IBS with mixed constipation and diarrhea (IBS-M)

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9
Q

What will you find on physical exam of a patient with IBS?

A

Normal exam

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10
Q

IBS is a dx of exclusion, which means?

A

Provider should r/o other disorders before considering dx

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11
Q

When should labs be done for IBS?

A

Not required unless suspicious of other dx

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12
Q

What imaging should be considered in patients with IBS?

A

Young patients: colonoscopy not recommended w/o alarming sx
50+: colonoscopy should be obtained to r/o malignancy

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13
Q

What diets may patients with IBS benefit from?

A

FODMAPs, low in fermentable oligo-, di-and monosaccharides and polyols
Lactose and gluten avoidance as well

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14
Q

What medications can be given for IBS-D?

A

Loperamide

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15
Q

What can be given for IBS-C?

A

Osmotic laxatives

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16
Q

What works best for treating IBS-D?

A

Tricyclic Antidepressants (TCA)
Amtriptyline or Imipramine