Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Gastrointestinal > Inflammatory Bowel Disease > Flashcards

Inflammatory Bowel Disease Flashcards

1
Q

What 2 conditions are included in Inflammatory Bowel Disease?

A

UC and Crohn’s

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Inflammatory bowel disease is a lifelong illness found to have what impacts on an individual?

A

Emotional and social impacts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

In Ulcerative Colitis(UC), where is inflammation limited to?

A

Colonic mucosa: mucosal inflammation
Can also have pseudo-polyps

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Where in the GI tract can Crohn’s manifest and what kind of lesions does it have?

A

Anywhere in the GI tract from mouth to anus
“Skip Lesions”

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Crohn’s disease and UC is associated with what percentage of patients with a number of extra-intestinal manifestations?

A

50%, especially Crohn’s

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What extra intestinal manifestations do Crohn’s and UC share?

A

Erythema nodosum, pyoderma gangrenosum, thromboembolic events

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What extra- intestinal manifestations are specific to Crohn’s?

A

Oral Ulcers, anorectal disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What extra- intestinal manifestations are specific to UC?

A

Peripheral arthritis, spondylitis or sacroiliitis, episcleritis or uveitis, hepatitis and sclerosing cholangitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

UC has inflammation of which layer of bowel wall?

A

Mucosal layer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Crohn’s disease has inflammation which layer of bowel wall?

A

Transmural inflammation, complete inflammation of all layers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the most common portion of the GI tract Crohn’s affects?

A

Terminal ileum which results in malabsorption of food, B12, bile salts and calcium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Physical findings of Crohn’s?

A

Ileitis or ileo-colitis
Non bloody, intermittent diarrhea
Weight loss (evidence of malnutrition)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is a complication of Crohn’s Disease?

A

Small Bowel obstruction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

One third of patients with large or small bowel involvement with Crohn’s disease develop what?

A

Perianal disease such as:
Anal fissures, abscesses, skin tags, fistulas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What lesions are common with Crohn’s disease?

A

Oral Aphthous ulcers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Crohn’s disease increases the prevalence of what due to malabsorption of bile salts?

A

Gallstones (cholelithiasis)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What other stones may form due to Crohn’s?

A

Kidney stones (nephrolithiasis)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What kind of onset does Crohn’s have?

A

Insidious with bouts of fever, diarrhea and RLQ pain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

How many cases of Crohn’s involve small bowel only, usually the terminal ileum (ileitis)?

A

1/3 of cases

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

How many cases of Crohn’s involve small bowel and colon (ileocolitis)?

A

Half of all cases

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

What social action is strongly associated with the development of Crohn’s disease?

A

Cigarette smoking

22
Q

What labs should be done for patients with Crohn’s?

A

CBC w/ serum albumin

23
Q

What is the treatment directed towards in Crohn’s?

A

Symptomatic relief

24
Q

What therapies are available for Crohn’s?

A

5- aminosalicylic acid derivatives (5-ASA)
Corticosteroids
Immuno-modulating and biologic agents

25
Q

Acute flairs of Cron’s may require what intervention?

A

Surgical intervention (i.e. bowel perforation)

26
Q

What products should you counsel Crohn’s patients to discontinue?

A

Tobacco products

27
Q

Who should you consult for Crohn’s patients?

A

GI/Gen surg

28
Q

Is bleeding/severe hemorrhage common in patients with Crohn’s?

A

No, it is unusual

29
Q

When should patients with Crohn’s begin screening colonoscopy?

A

8 or more years after initial flare/dx

30
Q

How much more likely are patients with Crohn’s likely to develop colon cancer than the rest of the population?

A

20x more likely

31
Q

UC or Crohn’s have a higher risk of development of carcinoma?

A

UC

32
Q

What is thought to cause UC?

A

Abnormal activation of immune system resulting in diffuse inflammation of colonic mucosa (mucosa of large intestine)

33
Q

UC involves what structures?

A

Only mucosa of large intestine
Can involve the rectum (begins distally and migrates proximally)

34
Q

UC commonly extends to which parts of the large intestine?

A

Proximal portion to involve part or all of large intestine

35
Q

What is common in UC that is not common in Crohn’s?

A

Bleeding

36
Q

What percentage of patients have UC confined to recto-sigmoid colon, splenic flexture (left sided colitis) and extensive colitis (proximal)

A

33% each

37
Q

UC is more common in what population?

A

Non smokers and former smokers

38
Q

What procedure before the age of 20 is associated with a lower risk of developing UC?

A

Appendectomy

39
Q

What signs and sx of infectious colitis, such as diverticulitis, mimic UC?

A

Bloody diarrhea
Fecal urgency

40
Q

What hx should be collected from patients with suspected UC?

A

Stool frequency/character
Prescence and amount of rectal bleeding
Diffuse crampy abdominal pain
Fecal Urgency
Tenesmus (needing to poopoo)

41
Q

What is the hallmark sx of UC?

A

Bloody diarrhea

42
Q

How do you classify patients with UC?

A

Mild, Moderate, Severe

43
Q

What are sx of mild UC?

A

Gradual onset infrequent diarrhea (less than 5 movements per day)
LLQ cramps relieved by defecation

44
Q

What are sx of moderate UC?

A

More severe diarrhea with frequent bleeding
Systemic sx

45
Q

What are sx of severe UC?

A

More than 6-10 blood bowel movements per day
Severe anemia, hypovolemia and impaired nutrition with hypoalbuminemia

46
Q

What labs should be done for patients with UC?

A

CBC, ESR, CRP, stool bacterial culture, C Diff, Ova and Parasites, serum albumin and electrolytes

47
Q

When should patients with UC begin colonoscopy screenings?

A

8 years after initial dx or initial flare

48
Q

What are the 2 main treatment objectives when treating UC?

A

Terminate acute, symptomatic attack
Prevent recurrence of attacks

49
Q

What medications are available for UC?

A

Mesalamine
Corticosteroid
Aminosalicylates
Antidiarrheals

50
Q

What surgical intervention may be required in severe case of UC?

A

Total proctocolectomy

Gastrointestinal (25 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions