Ipratropium Bromide (Atrovent)

Question 1

Classification

Answer 1

Bronchodilator, anticholinergic

Question 2

Mechanism of Action

Answer 2

• Antagonizes the acetylcholine receptors on the bronchial smooth muscle, producing bronchodilation

Question 3

Indications

Answer 3

• Asthma
• Bronchospasm associated with COPD

Question 4

Contraindications

Answer 4

• Closed angle glaucoma
• Bladder neck obstruction
• Prostatic hypertrophy
• Known sensitivity, including peanuts, soybeans, and atropine or atropine derivatives

Question 5

Adverse Effects

Answer 5

• Paradoxical acute bronchospasm

Question 6

Administration

Answer 6

• Adult: 0.5 mg every 6-8 hours nebulized

Question 7

Special Considerations

Answer 7

• Not typically used as the sole medication in the treatment of acute exacerbation of asthma. Commonly administered after a beta agonist.
• Take care to prevent aerosol spray from coming in contact with the eyes as this can cause temporary blurring of the vision.