Introduction to Metabolism Flashcards
What is metabolism?
Metabolism - by which an organism extracts energy from their environment and use this to synthesise large molecules
Why is metabolism important in our daily lives?
Good health depends on a well-balanced metabolism Many disorders involve changes in the balance of metabolic activated (e.g. - Diabetes, obesity or vitamin deficiencies)
How much oxygen does the resting human have and how much does this go up by when exercising?
Resting human - approx 250m O2/min (1.25 litres / 5 mins) Can increase 5 times during exercise
What is oxygen used for in the body?
Oxygen is used to oxidise substrates and produce energy for the body’s needs
What is the definition of oxidation?
Oxidation is the addition of oxygen to molecules - Also the removal of electrons
What is the definition of reduction?
Reduction is the removal of oxygen from molecules - Also addition of electrons
What acronym is used two remember what one loses and gains electrons?
OIL RIG; Oxidation Is Loss of electrons Reduction Is Gain of electrons
What is the definition of catabolism?
Catabolism - Breakdown of large molecules to smaller ones, releasing energy
What is the definition of anabolism?
Anabolism - Process by which large molecules are built from smaller ones, requires an energy input
How can anabolism and catabolism work together?
The energy produced by catabolism is used to drive anabolism and other energy-requiring processes
What does delta G stand for?
Change in free energy
What always happens in chemical reactions?
An absorption or release of energy
For the reaction of A + B C + D, what is the formula to work out the change in free energy (delta G)?
(Delta) G = (Delta)G^o + RT loge [C][D]/[A][B] (Delta) G = Free energy change for the reaction with reactants at the concentrations given (Delta) G^o = Standard free energy change (when all reactants are present at a concentration of 1.0 M) R = Gas constant T = Absolute temperature
What is the only way that a reaction can occur spontaneously without an energy input ?
If the free energy change (Delta G) is negative between the starting materials and final products
What does the magnitude of delta G not indicate ?
How rapidly the reaction will take place