integumentary Flashcards

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1
Q

what is the outermost layer of skin know as

A

skin epidermis

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2
Q

name the 4 major cells found in the epidermis

A

keratinocytes, melanocytes, Merkel cells and dendritic cells

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3
Q

what is the role of keratinocytes

A

produce keratin, born deep is epidermis and flatten as they move up to surface of skin, the main cell type in the epidermis

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4
Q

the role of melanocytes

A

secrete melanin and found in the deepest layer of the epidermis

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5
Q

the role of Merkel cells

A

specialised in sensory aids like - light touch and texture

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6
Q

the role of dendritic cells

A

activate immune defence and injest invaders/ foreign materials

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7
Q

name the other major layer of the skin

A

skin dermis

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8
Q

what are the 2 sublayers of the dermis

A

papillary layer and the reticular layer

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9
Q

name structure of the papillary layer

A

loose areolar connective tissue (elastic fibres loose and stretchy)

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10
Q

name the structure of the reticular layer

A

dense irregular connective tissue (made of collagen so very tough and strong)

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11
Q

name the 6 features found overall in the dermis

A

collagen, elastic fibres, blood vessels, nerve endings, sweat glands, hair follicles

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12
Q

name the 4 main functions of the skin

A

protection, temperature regulation, secretion, cutaneous sensation

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13
Q

name 3 things the skin must provide protection against

A

infection, physical damage(UV), chemical damage/ dehydration

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14
Q

name 2 ways in which the skin monitors temp

A

hair follicles- trap layer of air to insulate and sweat glands- evaporations help cooling

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15
Q

name 2 glands found in the skin that secrete

A

sebaceous gland- secreting oil and apocrine gland- secretes milky/oil producing sexual scent

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16
Q

name two features in the skin allowing for cuteness sensation

A

free nerve ends- touch/pain/temp and pacinlan corpuscle- vibration and pressure

17
Q

name the 4 stages of soft tissue repair

A
  1. haematoma, 2.scab formation, 3.granulation phase, 4. regeneration and remodelling
18
Q

name 3 things that occur in the haematoma phase of STR

A
  1. inflammatory chemicals released, 2. local blood vessels become leaky, 3. WBC, fluid and clotting proteins seep into damaged area
19
Q

name 2 tings that occur in scab formation in STR

A
  1. clot seals injured area from infection, 2. clot dries and forms scab
20
Q

name 4 things that occur in granulation phase in STR

A
  1. ingrowth of fragile capillaries replace scab, 2. fibroblasts multiply and produce collagen fibres and growth factors, 3. macrophages phagocytise dead cells and debris, 4. surface epithelial begins to multiply over granulation tissue
21
Q

name 3 things that occur in regeneration and remodelling phase of STR

A
  1. fibroses area contracts pulling wound together, 2. epithelium thickens under scab that then detaches, 3. fully generated epidermis with scar-tissue underneath.
22
Q

name the 4 stages of bone repair

A

haematoma, soft callus, hard callus and remodelling

23
Q

name e the 2 things that happen in haematoma phase of BR

A

blood vellsel in bone and periosteum are torn, 2. bone cells become starved and die, causing cell death and swelling and haematoma forms

24
Q

name the 3 stages in soft callus formation in BR

A

1.fibroblasts and chondroblasts invade site, 2. fibroblasts produce collagen connecting ends of bone, 3. chondroblasts produce cartilaginous matrix that then calcifies forming soft callus (fibro-cartillaginous callus)

25
Q

name the 3 stages in soft callus formation in BR

A

1.fibroblasts and chondroblasts invade site, 2. fibroblasts produce collagen connecting ends of bone, 3. chondroblasts produce cartilaginous matrix that then calcifies forming soft callus (fibro-cartillaginous callus)

26
Q

name the 3 stages in hard callus formation in BR

A

1.osteoblasts begin to form spongey bone, 2. trabeculae spans the callus and unites the two beaks, 3. soft callus slowly replaced by mature bone, converting to hard callus

27
Q

name the 3 stages in remodelling in BR

A

remodelling begins during hard callus stage, 2. excess material removed from diaphysis exterior and medullary cavity, 3. compact bone layer down to reconstruct shaft walls.

28
Q

what is colouration of the skin caused by

A

haemoglobin, melanin, carotene

29
Q

name 3 abnormal colourations of the skin

A

cyanosis, jaundice, albinism, haematoma, pallor