immunity Flashcards
what are the 2 major groups for primary defence
mechanical and chemical
name 2 mechanical defences
skin and mucous membrane
name chemical defences
stomach acid and lysozyme (in tears and saliva)
name the 5 major secondary defences
antimicrobial proteins, natural killer cells, phagocytes, inflammation and fever
name 2 antimicrobial proteins
stomach interferon and transferrins
name the purpose of nk cells
destroy cells by perforating the plasma membrane
role of phagocytes
engulf foreign cells
role of fever as secondary defence
increasing internal temp enhances interferon and inhibits microbial growth, speeding up repair
what are the 2 types of lymphocytes
B-lymphocytes and T-lymphocytes
what do B-cells produce
antibodies known as immunoglobulins
name the 5 different antibodies
REMEMBER- GAMED
igG- main antibody igA- secretory antibody igM- released into plasma igE- associated with allergies and igD- attached to b-cell and acts as antigen receptor
where do b-cells develop their immunocompetence
red bone marrow
what are t-cells role
to mediate immune response
what is one thing t-cells develop into
T killer-cells that can directly attack invading pathogen
what is the other thing t-cells develop into
t helper-cells that help both antibody and cells response