immunity Flashcards

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1
Q

what are the 2 major groups for primary defence

A

mechanical and chemical

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2
Q

name 2 mechanical defences

A

skin and mucous membrane

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3
Q

name chemical defences

A

stomach acid and lysozyme (in tears and saliva)

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4
Q

name the 5 major secondary defences

A

antimicrobial proteins, natural killer cells, phagocytes, inflammation and fever

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5
Q

name 2 antimicrobial proteins

A

stomach interferon and transferrins

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6
Q

name the purpose of nk cells

A

destroy cells by perforating the plasma membrane

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7
Q

role of phagocytes

A

engulf foreign cells

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8
Q

role of fever as secondary defence

A

increasing internal temp enhances interferon and inhibits microbial growth, speeding up repair

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9
Q

what are the 2 types of lymphocytes

A

B-lymphocytes and T-lymphocytes

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10
Q

what do B-cells produce

A

antibodies known as immunoglobulins

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11
Q

name the 5 different antibodies

A

REMEMBER- GAMED
igG- main antibody igA- secretory antibody igM- released into plasma igE- associated with allergies and igD- attached to b-cell and acts as antigen receptor

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12
Q

where do b-cells develop their immunocompetence

A

red bone marrow

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13
Q

what are t-cells role

A

to mediate immune response

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14
Q

what is one thing t-cells develop into

A

T killer-cells that can directly attack invading pathogen

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15
Q

what is the other thing t-cells develop into

A

t helper-cells that help both antibody and cells response

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16
Q

which lymphocytes produce memory cells

A

both T and B cells do

17
Q

what do memory cells allow for

A

they allow for second response to be more efficient

18
Q

what do memory cells have a memory of

A

the invading antigen

19
Q

what are the two types of immunity classified as

A

active immunity and passive immunity

20
Q

explain a naturally acquired active immunity

A

being infected by contact with pathogen

21
Q

explain an artificially acquired passive immunity

A

immune injection (gamma globulin)

22
Q

define autoimmune response

A

the body fails to recognise self from non-self and attacks own cells

23
Q

name 2 autoimmune disease

A

ms- multiple sclerosis- destroys myelin of nerve system and rheumatoid arthritis- destroys cartilage of own joint

24
Q

another term used for allergies

A

hypersensitivity

25
Q

what are the antigens called that cause allergy

A

allergen

26
Q

why does an allergy occur

A

somebody reacts to a substance normally tolerated by most others