Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

***Roitt's essential immunology > Innate immunity > Flashcards

Innate immunity Flashcards

1
Q

1. Which of the following does NOT protect body surfaces?

A Skin

B Mucus

C Gastric acid

D Salivary amylase

E Gut microflora

A

D Salivary amylase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

2. Pattern recognition receptors (PRR) include which of the following?

A Lipopolysaccharide (LPS)

B Pathogen-associated molecular patterns (PAMPs)

C Lipoteichoic acid

D Lectin-like molecules

E Unmethylated CpG sequences

A

D Lectin-like molecules

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

3. Which of the following does the mononuclear phagocyte system NOT include?

A Monocytes

B Kupffer cells

C Kidney mesangial cells

D Lymph node medullary macrophages

E Endothelial cells

A

E Endothelial cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

4. A polymorphonuclear neutrophil (PMN):

A Is a bone marrow stem cell

B Is closely similar to a mast cell

C Contains microbicidal cytoplasmic granules

D Is not a professional phagocytic cell

E Has granules that stain with eosin

A

C Contains microbicidal cytoplasmic granules

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

5. Which of the following is NOT produced following activation of the NADPH oxidase microbicidal pathway?

A O2−

B O2

C H2O2

D NO

E OH

A

D NO

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

6. Neutrophil defensins are:

A Anti-toxins

B Oxygen-dependent

C Enzymes

D Glycolipids

E Peptide antibiotics

A

E Peptide antibiotics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

7. The Toll-like receptor 9 (TLR9) pattern recognition receptor recognizes:

A CpG motifs

B Bacterial lipopeptides

C Lipoteichoic acid

D Gram-negative LPS

E dsRNA

A

A CpG motifs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

8. Complement component C3 is cleaved by:

A C3b

B C3bBb

C Factor B

D Factor D

E Factor H

A

B C3bBb

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

9. The membrane attack complex consists of:

A OH

B Colicins

C C3bBb3b

D C5b,6,7,8,9

E Properdin

A

D C5b,6,7,8,9

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

10. Which of the following statements is TRUE of C3b?

A C3b is chemotactic for neutrophils

B C3b is an anaphylatoxin

C C3b opsonizes bacteria

D C3b directly injures bacteria

E C3b is the inactive form of C3

A

C C3b opsonizes bacteria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

11. Acute inflammation characteristically involves:

A Constriction of arterioles

B Capillary endothelial cell enlargement

C Influx of macrophages

D Influx of mast cells

E Influx of neutrophils

A

E Influx of neutrophils

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

12. Which of the following statements is TRUE of lysozyme?

A Lysozyme is a cytoplasmic organelle

B Lysozyme activates complement

C Lysozyme is a proteolytic enzyme

D Lysozyme splits peptidoglycan

E Lysozyme is released by mast cells

A

D Lysozyme splits peptidoglycan

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

13. Which of the following is NOT an acute phase protein?

A Serum amyloid P component

B Chondroitin sulfate

C C-reactive protein

D Mannose-binding lectin

E Fibrinogen

A

B Chondroitin sulfate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

14. Which of the following statements is TRUE of interferons?

A Interferons are found only in mammalian species

B Interferons are divided into five main families

C Interferons induce enzyme synthesis in the target cell

D Interferons only affect infected cells

E Interferons are specific for individual viruses

A

C Interferons induce enzyme synthesis in the target cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

15. Natural killer (NK) cells do NOT:

A Respond to interferon

B Contain perforin

C Contain tumor necrosis factor (TNF)

D Kill only by damaging the target cell outer membrane

E Contain serine proteases

A

D Kill only by damaging the target cell outer membrane

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

16. Eosinophils do NOT:

A Stain with basic dyes

B Contain a major basic protein

C Contain peroxidase

D Give a respiratory burst on activation

E Have C3b receptors

A

A Stain with basic dyes

17
Q

17. Polymorphonuclear neutrophils attack bacteria:

A Exclusively by oxygen-dependent mechanisms

B Exclusively by oxygen-independent mechanisms

C By phagocytosis

D By secreting complement

E By secreting interferon

A

C By phagocytosis

18
Q

18. Which of the following is a complement component that is strongly chemotactic for neutrophils?

A C9

B C5a

C C3

D C3b

E C5b

A

B C5a

19
Q

19. Acute inflammation can be initiated by:

A Mast cell activation

B Influx of neutrophils

C An increase in vascular permeability

D C3

E Lysozyme

A

A Mast cell activation

20
Q

20. The NLRP3 inflammasome leads to the release of:

A IL-8

B IL-1β

C TNF

D Interferon-α

E Platelet activating factor (PAF)

A

B IL-1β

***Roitt's essential immunology (17 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions