Injectable Anesthetics Flashcards

1
Q

What are the priorities for induction of anesthesia?

A

Rapidly secure airways and give oxygen
Maintain cardiovascular function
Induce/maintain anesthesia

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2
Q

Ketamine

A
Relatively safe anesthetic
Analgesic effect
Increases cerebral blood flow and volume
Catatonic state
Cause Dysphoria
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3
Q

What receptors does Ketamine act on?

A

NMDA receptors - Antagonist

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4
Q

CV effects of Ketamine

A

Negative inotropy
catecholamine release
increases in HR and contractility

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5
Q

Respiratory effects of Ketamine

A

Minimal respiratory depression
Apneustic breathing
Bronchodilation

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6
Q

Factors increasing cerebral blood volume

A
Hypercapnia
Hypoxia
Hypertension
Coughing 
vomiting
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7
Q

CNS effects of ketamine

A

Cerebral vasodilation: intracerebral volume and pressure increase ICP

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8
Q

Other effects of Ketamine

A

Muscle tone increased
Increased salivation
Open eyes
Intraocular pressure increases

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9
Q

CV effects of Propofol

A

Vasodilation

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10
Q

Respiratory effects of Propofol

A

Apnea

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11
Q

CNS effects of Propofol

A

Intracerebral blood volume and ICP decreases
Cerebral metabolic O2 consumption decreases
antiepileptic effect

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12
Q

Propofol in cats

A

May cause hemolysis and Heinz body anemia

Pain during injection

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13
Q

What is the drug of choice for C-sections?

A

Propofol

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14
Q

What is the most common induction agent?

A

Propofol

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15
Q

What is the distribution order of thiopental?

A
  1. Vessel rich group
  2. Muscle Group
  3. Fat group
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16
Q

CV effects of Thiopental?

A

Negative inotropy
Vasodilation
Arrhythmogenic

17
Q

What is a good choice for neurosurgery as induction agent?

A

Thiopental

18
Q

Etomidate

A

Minimal CV effects
NO ANALGESIA
Moderate muscle relaxation

19
Q

CV effects of Etomidate

A

Not arrhythmogenic

20
Q

CNS and Respiratory effects of Etomidate?

A

No analgesic effect

May produce or terminate seizures

21
Q

Other effects of Etomidate

A

Vomiting
excitement and twitching
Pain
Hemolysis

22
Q

Alfaxalone

A

Minimal CV effects
No analgesia
Good Muscle Relaxation

23
Q

CV effects of Alfaxalone

A

Little or no CV effects