Infectious Diseases Flashcards
1
Q
Examples of infectious agents
A
Bacteria, virus, fungi, parasite, prions (infectious particle with no DNA or RNA)
2
Q
How do organisms cause disease?
A
Living in tissues.
Release toxins.
3
Q
How do viruses damage tissue?
A
Direct cytopathic effects (structural changes to host cell)
Immune Reactions
Incorporation of viral genes into host genome.
4
Q
How do bacteria damage tissue?
A
Aggressins - non-toxic material which enhance the survival of the organism.
E.g. Coagulase - promotes blood clotting on the surface and forms a protective “coat” around itself.
Streptokinase - promotes plasminogen activation, decreasing clotting and healing.
5
Q
What are the signs/symptoms of Sepsis?
A
Temp: 38.3+ or 36- HR: 90bpm + RR: 20 breaths pm + Decreased urine output Abrupt change in mental status Decreased platelet count Difficulty breathing Abnormal heart pumping function Abdo pain
