Important Drug Info Flashcards
ativan onset
1-5 min iv; 15-30 min im
ativan peak
15-20 min iv; 2 hr im
ativan duration
6-8 hrs
ativan adult dose
0.5mg-2mg IV or 1-4mg IM
ativan pedi dose
0.05 mg/kg IV
benzo precautions
additive effects with other CNS depressants, ETOH
versed onset
3-5 min IV, 15 min IM
versed peak
20-60 min
versed duration
<2hrs IV, 1-6 hrs IM
versed adult dose
2-5 mg IV/IM
versed pedi dose
0.2 mg/kg slow IV
albuterol onset
5-15 min
albuterol peak
1-1.5 hrs
albuterol duration
3-6 hrs
albuterol contraindications
symptomatic tachycardia
albuterol dose
2.5 mg in 2.5 mL
albuterol interactions
b-blockers blunt effects, MAOI’s and TCA’s potentiate cardiovascular effects
albuterol MOA
B2 agonist
atrovent drug class
anticholinergic/parasympatholytic
atrovent moa
muscarinic Ach-R blocker, dries resp. secretions
atrovent onset
varies
atrovent peak
1.5-2 hrs
atrovent duration
4-6 hrs
atrovent adult dose
500 mcg
atrovent pedi dose
250-500 mcg
mag sulfate drug class
mineral/antidysrhythmic
mag sulfate moa
physiological ca+ channel blocker, CNS depression, smooth muscle relaxation
mag onset
immediate IV
mag peak
varies
mag duration
1 hr
mag contraindications
3rd degree block, severe hypertension, impaired renal function, hypocalcemia
mag SE
flushing, sweating, bradycardia, resp. depression, dysrhythmias, hypotension
mag precautions
watch for resp. depression, have cacl2 available
mag interactions
digitalis
mag adult asthma dose
2g in 100cc NS over 10 min
mag adult VT, VF, Torsades (no pulse) dose
2g IV over 1-2 min
mag adult VT/torsades w/ pulse dose
1-2g in 50-100 CC NS over 5-60 min
mag eclampsia dose
2-4g over 25 min
mag pedi asthma dose
25-50 mg/kg over 15-30 min (max of 2g)
mag pedi VT no pulse dose
25-50 mg/kg IV (2g max)
mag pedi VT w/ pulse
25-50 mg/kg IV over 10-20 min (max 2g)
solu-medrol drug class
corticosteroid/immunosuppressant
solu-medrol onset
2-6 hrs
solu-medrol peak
4-8 days
solu-medrol duration
1-5 weeks
solu-medrol SE
Prolonged wound healing
solu-medrol adult dose
125mg
solu-medrol pedi dose
2mg/kg IV (max 80mg)
solu-medrol precautions
prolongs wound healing
solu-medrol interactions
lasix and thiazide diuretics increase K+ loss
nitro MOA
vasodilator, decreases preload and afterload
nitro onset
1-3 min SL
nitro peak
5-10 min SL
nitro duration
20-30 min SL
nitro contraindications
systolic under 100; R sided MI, ED drugs in past 48 hrs
nitro dose
0.4 mg SL q3-5 (max 3 doses or until systolic under 100)
nitro interactions
B-blockers cause orthostatic hypotension, ETOH causes severe hypotension
epi onset
<2 min IV; 3-10 min IM
epi peak
<5 min; 20 min IM
epi duration
5-10 min IV; 20-30 min IM
epi contraindications
HTN, tachydysrhythmias, pregnancy
epi interactions
deactivated by alkali, antidepressants intensify effects, forms PPT with CaCl2 and bicarb
aspirin moa
cox inhibitor, platelet aggregation inhibitor
aspirin onset
5-30 min
aspirin peak
15-120 min
aspirin duration
1-4 hrs
morphine onset
imm IV, 15-30 IM
morphine peak
20 min IV, 30-60 IM
morphine duration
2-7 hrs
morphine contraindications
hypotension/hypovolemia, COPD, hypersensitivity to morphine, codeine, percodan
morphine adult dose
2-10mg initial then 2mg q3-5min
morphine pedi dose
0.1mg/kg
morphine interactions
additive effects with CNS depression
zofran onset
10-30 min
zofran peak
unknown
zofran duration
unknown
zofran adult dose
4mg
zofran pedi dose
0.1mg/kg
adenosine drug class
class V antidysrhythmic
adenosine MOA
slow AV conduction
adenosine onset
imm.
adenosine peak
imm.
adenosine duration
30-45 sec
adenosine contraindications
2/3rd degree block, sick sinus syndrome, chemical induced SVT
adenosine adult dose
6mg then 12mg then 12mg
adenosine pedi dose
0.1mg/kg (max 6mg) then 0.2mg/kg (max 12mg)
epi moa
a1, b1, b2 agonist, blocks destruction of mast cells
epi drip dose
2-10 mcg/min
amiodarone class
class III, K+ channel blocker
amiodarone moa
prolongs cardiac action potential duration, refractory period
amiodarone onset
immed.
amiodarone SE
prolonged PR, QRS, QT intervals
amiodarone VT with pulse dose
150mg over 10 min
amiodarone pedi dose
5mg/kg, max 300mg
amiodarone VT w/ pulse pedi dose
5mg/kg over 20-60 min max 300mg
atropine moa
ach-r antagonist, parasympathetic inhibition; positive chronotropy but no inotropic effect
atropine onset
immed.
atropine peak
2-4 min
atropine duration
4 hrs
atropine bradycardia dose
.5 mg q3-5 min max 3mg
atropine RSI dose
.5-1mg
atropine OP OD dose
2-5 mg
atropine pedi bradycardia dose
0.02mg/kg min 0.1 max 0.5mg
atropine pedi RSI dose
0.02mg/kg
atropine OP OD dose pedi
0.02-0.05mg/kg
atropine contraindications
ineffective for 2nd degree type II/3rd degree blocks
atropine precautions
don’t give less than 0.1mg (pedi) or 0.5mg (adult)
cardizem moa
slows av conduction, ca2+ channel blocker, decrease inotropy
cardizem onset
3min
cardizem duration
1-3 hrs
cardizem indications
rapid a-fib, a-flutter, PSVT refractory to adenosine
cardizem SE
N+V, dizziness, HA, bradycardia, heart block, hypotension, asystole
cardizem dose
15, 20, or 25mg
cardizem precautions
not for pedi!, may cause hypotension, have cacl2 available
cardizem contraindications
do not give to Pt’s getting IV b blockers
calcium chloride moa
increases myocardial contractility and ventricular automaticity
cacl2 indications
hyperkalemia, hypocalcemia, ca+ channel blocker OD, crush syndrome, hypermagnesemia, CA due to suspected hyperkalemia
cacl2 SE
bradycardia, dysrhythmias, N+V, syncope, CA
cacl2 adult dose
500-1000mg
cacl2 pedi dose
20mg/kg
cacl2 precautions
tissue necrosis
cacl2 interactions
forms PPT with bicarb
