Drug Quiz 6 - ACLS Drugs Flashcards
Cacl2 drug class
mineral/electrolyte
Cacl2 moa
increases myocardial contractility and ventricular automaticity
Cacl2 onset of action
immediate
Cacl2 peak effects
unknown
Cacl2 duration of effect
varies
Cacl2 half life
n/a
Cacl2 indications
hyperkalemia, hypocalcemia, ca2+ channel blocker toxicity, crush syndrome, hypermagnesemia, abdominal muscle spasms from brown recluse spiders or man of war jellyfish, CA secondary to suspected hyperkalemia or known dialysis pt
Cacl2 contraindications
hypercalcemia
Cacl2 side effects
bradycardia, respiratory depression, syncope, cardiac arrest
Cacl2 adult dose
8-16mg/kg or 500-1000 mg
Cacl2 pedi dose
20mg/kg
Cacl2 precautions
tissue necrosis, digitalis toxicity
Cacl2 drug interactions
ppt with nahco3, digitalis toxicity
dopamine hcl trade name
intropin
intropin generic
dopamine hcl
dopamine moa
a1 and b1 agonist
dopamine onset of action
<5 min
dopamine peak effects
5-8 min
dopamine duration of effect
<10 min
dopamine half life
2 min
dopamine indications
hypotension not called by hypovolemia, cardiogenic shock, symptomatic bradycardia
dopamine contraindications
hypovolemic shock where fluid have not been administered to maximum capacity, patients with adrenal gland tumor, tachydysrhythmias and VF
dopamine side effects
headache, dysrhythmias, palpitations, chest pain
dopamine low dose
2-5mcg/kg/min increases blood flow to gut
dopamine medium dose
5-10mcg/kg/min stimulates b1 effects
dopamine high dose
10-20mcg/kg/min stimulates a1 effects
dopamine precautions
protect from light
dopamine drug interactions
deactivated by alkaline solutions, maoi, hypotension with dilantin
mag s+ulfate drug class
electrolyte/mineral
mag sulfate moa
ca2+ channel blocker, causes cns depression and smooth muscle relaxation
mag onset of action
immediate iv, 1 hr im
mag peak effects
varies
mag duration of effect
1 hr
mag half life
n/a
mag indications
severe asthma, refractory VF or pulseless VT, torsades, post-mi prophylaxis, eclampsia
mag contraindications
3rd degree heart block, shock, severe hypertension, impaired renal function, hypocalcemia
mag side effects
bradycardia, respiratory depression, hypotension, flushing
mag adult asthma dose
2g in 100cc NS infused over 10 min
mag vt, vf, torsades no pulse adult dose
2g over 1-2 min
mag vt/torsades + pulse adult dose
1-2g in 50-100 cc NS, over 5-60 min
mag eclampsia dose
2-4g over 25 min
mag pedi asthma dose
25-50mg/kg over 15-30 min, max dose 2g
mag vt-no pulse pedi dose
25-50mg/kg max of 2g
mag vt+pulse pedi dose
25-50mg/kg max of 2g over 10-20 min
mag precautions
watch for resp. depression, have cacl2 available
mag drug interactions
digitalis
procainamide trade name
pronestyl
pronestyl generic name
procainamide
procainamide moa
na+ channel blocker, slows phases IV and 0 of cardiac cycle
procainamide onset of action
10-30 min
procainamide peak effects
15-20 min
procainamide duration of effect
3-6 hrs
procainamide half life
3 hrs
procainamide indications
persistent cardiac arrest secondary to vf, pvc’s, and vt all refractory to lidocaine
procainamide contraindications
2/3rd degree heart blocks, pvc’s with bradycardia
procainamide side effects
hypotension, bradycardia, heart blocks, respiratory and cardiac arrest
procainamide adult dose
100mg q5min at 20mg/min; maintenance 1-4mg/min
procainamide pedi dose
15mg/kg over 30-60 min
procainamide precautions
monitor bp; dc if dysrhythmia is suppressed, hypotension occurs, qrs widens by 50%, or 17 mg/kg has been administered
procainamide drug interactions
hypotension when taken with antihypertensives, neurotoxicity with lidocaine
sodium bicarb drug class
alkalinizing agent/electrolyte
sodium bicarb moa
the bicarb buffer formula
sodium bicarb onset of action
immediate
sodium bicarb peak effects
<15 min
sodium bicarb duration of effect
1-2 hrs
sodium bicarb half life
n/a
sodium bicarb indications
metabolic but not respiratory acidosis; tricyclic antidepressant OD
sodium bicarb contraindications
tums OD and routine cardiac arrest
sodium bicarb side effects
none
sodium bicarb dose
1 mEq/kg IV
sodium bicarb precautions
causes metabolic alkalosis in large quantities
sodium bicarb drug interactions
deactivates catecholaines and vasopressors, forms PPT with CaCl2
vasopressin trade name
pitressin
pitressin generic name
vasopressin
vasopressin drug class
vasopressor/hormone
vasopression moa
V1 R agonist, releases ca2+ from sarcoplasmic reticulum, sustained contractions by VSMC leading to vasoconstriction
vasopressin onset of action
varies
vasopressin peak effects
varies
vasopressin duration of effects
30-60 min
vasopressin half life
10-20 min
vasopressin indications
increase peripheral vascular resistance during cpr
vasopressin contraindications
none
vasopressin side effects
dysrhythmia, bradycardia, blanching of skin, htn, nausea
vasopressin adult dose
40 units iv, single dose, to replace 1st or 2nd dose of epi
vasopressin pedi dose
none
vasopressin precautions
caution with pt’s with epilepsy, migraine, asthma, heart failure, angina; may increase myocardial o2 demand
vasopressin drug inteactions
none in acls