Drug Quiz 5 Flashcards by Steve Teigers

aspirin drug class

platelet aggregation inhibitor/anti-inflammatory

How well did you know this?

Not at all

Perfectly

aspirin MOA

blocks formaton of thromboxane A2 prevents platelet aggregation; cox inhibitor, inhibits prostaglandin synthesis

How well did you know this?

Not at all

Perfectly

aspirin onset of action

5-30 min

How well did you know this?

Not at all

Perfectly

aspirin peak effects

15-120 min

How well did you know this?

Not at all

Perfectly

aspirin duration of effect

1-4 hrs

How well did you know this?

Not at all

Perfectly

aspirin half life

15-20 min

How well did you know this?

Not at all

Perfectly

aspirin indications

chest pain suggestion of ami/acs

How well did you know this?

Not at all

Perfectly

aspirin contraindications

hypersensitivity, active ulcer, asthma

How well did you know this?

Not at all

Perfectly

aspirin side effects

gi bleeding, wheezing, n+v, heartburn

How well did you know this?

Not at all

Perfectly

aspirin adult dose

160-325mg

How well did you know this?

Not at all

Perfectly

aspirin pedi dose

not for pedi

How well did you know this?

Not at all

Perfectly

aspirin precautions

can cause gi upset/bleeding

How well did you know this?

Not at all

Perfectly

aspirin interactions

with other anti-inflammatories cause increased side effects; with antacid decreased absorption

How well did you know this?

Not at all

Perfectly

morphine drug class

narcotic analgesic

How well did you know this?

Not at all

Perfectly

morphine MOA

opiate R agonist, causes CNS depression, decreases preload and myocardial oxygen demand

How well did you know this?

Not at all

Perfectly

morphine onset of action

immediate iv, 15-30 min im

How well did you know this?

Not at all

Perfectly

morphine peak effects

20 min iv; 30-60 im

How well did you know this?

Not at all

Perfectly

morphine duration of effect

2-7 hrs

How well did you know this?

Not at all

Perfectly

morphine half life

1-7 hrs

How well did you know this?

Not at all

Perfectly

morphine indications

severe pain, pulmonary edema

How well did you know this?

Not at all

Perfectly

morphine contraindications

hypovolemia/hypotension; AMS; hypersensitivity; COPD/ compromised respiratory status

How well did you know this?

Not at all

Perfectly

morphine side effects

nausea/vomitting, constricted pupils, AMS, respiratory depression

How well did you know this?

Not at all

Perfectly

morphine adult dose

2-10mg iv initial, then 2mg q3-5

How well did you know this?

Not at all

Perfectly

morphine pedi dose

0.1mg/kg iv

How well did you know this?

Not at all

Perfectly

morphine precautions

respiratory depression, have narcan available

morhine interactions

additive effects with antihistamines, antiemetics, sedatives, hypnotics, barbituates, alcohol

ondansetron trade name

zofran

zofran generic name

ondansetron

zofran drug class

anti-emetic

zofran MOA

serotinin R antagonist, especially at vagal nerve terminals

zofran onset of action

10-30 min

zofran peak effects

unknown

zofran duration of effects

unknown

zofran half life

4 hrs

zofran indications

nausea/vomitting

zofran contraindications

hypersensitivity

zofran side effects

prolonged QT interval, HA, dizziness, tachycardia

zofran adult dose

4mg iv over 2-5 min

zofran pedi dose

0.1 mg/kg iv over 2-5 min

zofran precautions

lower risk of sedation and dystonia than other antiemetics

zofran drug interactions

may effect clearance and half life with inducers and inhibitors of cytochrome p-450 enzymes

nitro trade name

nitrostat

nitro MOA

pro drug converted to nitric oxide, activates conversion of GTP to cGMP + 2Pi in VSMC, reduces intracellular Ca2+ causing VSMC relaxation, decreasing preload and afterload

nitro onset of action

1-3 min SL, 30 min topical

nitro peak effects

5-10 min SL, varies topical

nitro duration of effect

20-30 min SL, 3-6 hrs topical

nitro half life

1-4 min

nitro indications

chest pain of cardiac origin, acute pulmonary edema/CHF

nitro contraindications

systolic<100; ICP, children under 12, ED drugs w/in 48 hrs

nitro side effects

HA, dizziness, hypotension, tachycardia

nitro spray dose

0.4mg SL q3-5 (max 3x25min)

nitro paste dose

0.5-1 inch

nitro tablet dose

0.4mg SL

nitro pedi dose

not for kids

nitro precautions

monitor vitals, 12 lead prior to administration, caution w/ R sided MI

nitro interactions

orthostatic hypotension w/ b-blockers, severe hypotension w/ alcohol

epinephrine trade name

adrenalin, epipen

epi drug class

sympathomimetic, catecholamine

epi moa

a1 agonist causing peripheral vasoconstriction; b1 agonist causing positive inotropy, chronotropy, dromotropy; b2 agonist causing bronchodilation; blocks destruction of MAST cells

epi onset of action

<2 min IV, 3-10 min IM

epi peak effects

<5 min IV, 20 min IM

epi duration of effect

5-10 min IV, 20-30 min IM

epi half-life

5 min

epi indications

cardiac arrest, anaphylaxis, symptomatic bradycardia

epi contraindications

HTN and tachydysrhythmias, caution with pregnancy and CAD

epi side effects

anxiety, HA, dysrhythmias, tremulousness

epi adult cardiac arrest dose

0.5-1mg iv [1:10,000] q3-5

epi pedi cardiac arrest dose

0.01mg/kg iv [1:10,000] q3-5

epi bradycardia/hypotension dose

2-10 mcg/min

epi anaphylaxis adult dose

0.3-0.5mg im [1:1,000], then 0.1mg [1:10,000] iv over 3 min

epi pedi anaphylaxis dose

0.01mg/kg im [1:1,000], then 0.01mg/kg [1:10,000 iv (max of 0.3mg)

epi precautions

protect from light

epi drug interactions

inactivated by alkalinity, effects intensified with antidepressants, forms ppt with CaCl2 and NaHCO3