Drug quiz 10 - crazy person drugs Flashcards

Haldol, Zyprexa, Narcan, Romazicon, Ativan

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1
Q

ativan generic name

A

lorazepam

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2
Q

lorazepam trade name

A

ativan

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3
Q

ativan drug class

A

benzodiazepine/sedative/anticonvulsant

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4
Q

ativan moa

A

positive allosteric modulator for GABA receptors, increases intracellular Cl- concentration leading to hyperpolarization of cell

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5
Q

ativan onset

A

1-5 min iv; 15-30 im

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6
Q

ativan peak

A

15-20 iv; 2 hrs im

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7
Q

ativan duration

A

6-8 hrs

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8
Q

ativan half life

A

10-20 hours

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9
Q

ativan indications

A

seizures, premed for cardioversion, anxiety

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10
Q

ativan contraindications

A

hypersensitivity

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11
Q

ativan SE

A

hypotension, drowsy, respiratory depression, N+V

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12
Q

ativan adult dose

A

0.5-2mg IV or 1-4 IM

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13
Q

ativan precautions

A

have benzo antagonist available

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14
Q

ativan interactions

A

additive effects with CNS depressants and alcohol

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15
Q

haloperidol trade

A

haldol

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16
Q

haldol generic

A

haloperidol

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17
Q

haldol moa

A

mesolimbic D1/D2 antagonist, depresses release of hypothalamic and hypophyseal hormones; depresses the reticular activating system

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18
Q

haldol onset

A

30-45 min

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19
Q

haldol peak

A

10-20 min

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20
Q

haldol duration

A

varies

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21
Q

haldol half-life

A

3-35 hrs

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22
Q

haldol indications

A

psychotic episode

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23
Q

haldol contraindications

A

other drugs, especially sedatives or other antipsychotics; dysophoria caused by Talwan

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24
Q

haldol SE

A

EPS, restlessness, insomnia, widened qt

25
Q

haldol adult dose

A

2-5mg IM q4-8hr or PRN

26
Q

haldol pedi dose

A

1-3mg IM q4hr or PRN, max of 0.15mg/kg/day

27
Q

haldol precautions

A

may impair physical and mental abilities, may cause orthostatic hypotension, may cause dystonia

28
Q

haldol interactions

A

with lithium may cause encephalopathic syndrome; may increase chance of hypotension when taken with antihypertensives; additive effects with depressants

29
Q

naloxone trade

A

narcan

30
Q

narcan generic

A

naloxone

31
Q

narcan drug class

A

narcotic antagonist

32
Q

narcan moa

A

competitive opiate R antagonist

33
Q

narcan onset

A

<2 min IV, 2-10 IM/ET

34
Q

narcan peak

A

<2 min IV; 2-10 IM/ET

35
Q

narcan duration

A

20-120 min

36
Q

narcan half-life

A

60-90 min

37
Q

narcan indications

A

respiratory depression caused by narcotics OD; coma of unknown origin; polypharmacy OD prior to RSI

38
Q

narcan contraindications

A

hypersensitivity

39
Q

narcan SE

A

hypotension, hypertension, ventricular dysrhythmias, seizures, n+v

40
Q

narcan adult dose

A

0.4-2mg q2-3min IV, IO, IM, IN, ET until respiratory status improves

41
Q

narcan pedi dose

A

0.1mg/kg IM max 2mg/dose

42
Q

narcan precautions

A

caution w/ Pt with physiological narcotic dependency, may induce withdrawal - including infants with addicted mothers

43
Q

narcan drug interactions

A

may induce narcotic withdrawal

44
Q

olanzapine trade

A

zyprexa

45
Q

zyprexa generic

A

olanzapine

46
Q

zyprexa drug class

A

antipsychotic

47
Q

zyprexa moa

A

SSRI, NE reuptake inhibitor with antipsychotic and anticholinergic effects

48
Q

zyprexa onset

A

<30 min

49
Q

zyprexa peak

A

6 hrs

50
Q

zyprexa duration

A

varies

51
Q

zyprexa half life

A

21-54 hrs

52
Q

zyprexa indications

A

acute psychosis and alzheimer’s

53
Q

zyprexa contraindications

A

hypersensitivity

54
Q

zyprexa SE

A

somnolence, myalgia, dizzy, tremor

55
Q

zyprexa adult dose

A

10mg IM

56
Q

zyprexa pedi dose

A

not established

57
Q

zyprexa precautions

A

caution with CV disease, predisposition to hypotension, and Parkinson’s disease; must be reconstituted in 3ml water prior to administration

58
Q

zyprexa drug interactions

A

potentiates hypotensive effects of antihypertensives