Drug Quiz 3 Flashcards
nitroglycerin trade name
nitrostat
nitrostat generic name
nitroglycerin
nitro drug class
vasodilator/nitrate
nitro MOA
pro-drug converted to nitric oxide, reduces intracellular Ca2+ in vascular smooth muscle muscle, decreases cardiac preload and afterload
nitro onset of effect
1-3 min SL; 30 min topical
nitro peak effects
5-10 min SL; varies topically
nitro duration of effect
20-30 min SL; 3-6 hrs topically
nitro half life
1-4 min
nitro indications
chest pain associated with angina or MI, pulmonary edema/CHF
nitro contraindications
hypotension, ICP, children under 12, ED drugs within last 48 hrs
nitro SE
headache, dizziness, tachycardia, hypotension
nitro adult spray dose
.4mg SL q3-5min, (max 3x25min)
nitro adult paste dose
0.5-1 inch
nitro adult tablet
0.4mg SL
nitro precautions
check vitals and 12 lead before and after, expect HA, use EXTREME CAUTION if R-sided MI
nitro drug interactions
orthostatic hypertension w/ b-blockers, severe hypotension with alcohol
oxygen drug class
gas
oxygen MOA
cells use it for breakdown of glucose
oxygen onset of action
immediate
oxygen peak effects
<1 min
oxygen duration of effect
<2 min
oxygen half life
n/a
oxygen indications
hypoxia, difficulty breathing, spo2<94%
oxygen contraindications
ROSC post CA w/ sp02>94%; chest pain, MI, cell injury or death with sp02>94%
oxygen side effects
free radicals in presence of injured tissues, causing cell death