Immunoproliferative Diseases

Question 1

This is a benign or malignant condition that results from a single clone of lymphoid-plasma cells producing elevated levels of a single class of immunoglobulin.

Answer 1

Monoclonal Gammopathy

Question 2

What is the other name for Multiple Myeloma?

Answer 2

Lytic Bone Disease

Question 3

What plasma cell neoplasm that leads to the overproduction of IgG and BJP protein is present?

Answer 3

Multiple Myeloma

Question 4

What is the other name for Waldenstrom’s macroglobulinemia?

Answer 4

LPL (Lymphoplasmacytic Lymphoma)

Question 5

What disease causes the infiltration of lymphoplasmacytic cells into the bone marrow, where there is an increase in IgM & Cryoglobulins?

Answer 5

Waldenstrom’s Macroglobulinemia

Question 6

The presence of monoclonal proteins but MM signs & symtoms are absent.

Answer 6

MGUS (Monoclonal Gammopathy of Undertermined Significance)

Question 7

What chains are only present in the Light Chain Disease?

Answer 7

kappa and lambda chains

Question 8

What proteins is present in Light Chain Disease?

Answer 8

Bence Jones Protein

Question 9

Heavy Chain Disease is also called?

Answer 9

Franklin’s Disease

Question 10

What disease leads to the overproduction of heavy chains, and no production of light chains?

Answer 10

Heavy Chain disease

Question 11

What is the most common HCD?

Answer 11

Alpha Chain Disease

Question 12

Alpha Chain Disease produces what type of immunoglobulin?

Answer 12

IgA

Question 13

What is the other term for Alpha Chain disease?

Answer 13

Mediterranean Lymphoma/ Immunoproliferative Small Intestinal Disease (IPSID)

Question 14

What disease consist 1 or more heavy chain classes and both light chain types?

Answer 14

Polyclonal Gammopathy