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Immunoserology > Hypersensitivity > Flashcards

Hypersensitivity Flashcards

1
Q

What antibody mediated in Type 1 hypersensitivity?

A

IgE

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2
Q

What antibody mediated in Type 2 hypersensitivity?

A

IgG/IgM

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3
Q

What antibody mediated in Type 3 hypersensitivity?

A

IgG/IgM

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4
Q

The release of Cytokines is a mechanism of what type of hypersensitivity?

A

Type 4 hypersensitivity

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5
Q

Allergic and anaphylactic reactions is associated in what type of hypersensitivity?

A

Type 1 hypersensitivity

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6
Q

Cytolysis due to antibodies & complement is included in what hypersensitivity?

A

Type 2 hypersensitivity

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7
Q

What hypersensitivity that includes immune complex deposition?

A

Type 3 hypersensitivity

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8
Q

What is the most sensitive test, in vivo for hypersensitivity, that uses a needle to introduce a drop of allergen into the upper layer of skin of the forearm or back?

A

Percutaneous/Prick/Puncture Test

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9
Q

A positive result in the Puncture/Percutaneous Test demonstrates what?

A

Wheal & Flare (3-4 mm)

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10
Q

In the Intradermal test, after 15-20 mins. a positive result should show what characteristic?

A

Erythema & Wheal formation

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11
Q

How much antigen is administered to the inner forearm or upper arm of the patient in INtradermal Test?

A

0.01-0.05 mL

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12
Q

RAST (Radioallergosorbent test) is used to measure what specific immunoglobulin?

A

IgE

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13
Q

RIST (Radioimmunosorbent test) uses a radiolabeled IgE and what for a limited Ab binding site?

A

Patient IgE

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14
Q

Polyclonal AHG contains Abs directed to what substances?

A

IgG, C3b, C3d

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15
Q

Monoclonal AHG determines whether it is ____, _______, _______

A

IgG, C3b, C3d

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16
Q

How much time is needed to check for the redness in Patch testing?

A

48 hours

17
Q

Positive result in Patch Testing ?

A

Red with Papules

18
Q

How many units of PPD is injected intrademally using a syringe or fine needle in Mantoux method?

A

0.1 mL of 5 tuberculin units of PPD

19
Q

Mantoux method is examined between what hours?

A

48-72 hrs (2-3d)

20
Q

A positive Mantoux test shows what reaction?

A

> /= 5mm - HIV patient
/= 10mm - immigrants
/= 15 mm - individuals without risk factors

21
Q
A

Immunoserology (20 decks)

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