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Immunoserology > Autoimmune Disease > Flashcards

Autoimmune Disease Flashcards

1
Q

What are the autoantibodies of SLE?

A

ANA
anti-dsDNA, anti-DNP
anti-ENA, anti-Sm
Antiphospholipid Abs

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2
Q

Scleroderma AutoAbs?

A

Anti-centromere Ab
ANA

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3
Q

Sjogren’s Syndrome AutoAbs?

A

Anti-Salivary Duct Ab, Anti-Lacrimal Gland Ab, Antinuclear Ab, RA factor

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4
Q

RA AutoAbs?

A

RF - Ab to the Fc portion of IgG (IgM, IgG, IgA)

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5
Q

What is the autoab of Rheumatic Fever?

A

Anti-streptococcal Ab

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6
Q

What is the autoab of Post Streptococcal Glomerulonephritis?

A

Anti-Streptococcal Ab

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7
Q

What is/are the autoab of Goodpasture’s Syndrome?

A

Anti-basement membrane (alveolar, glomerular)

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8
Q

What is/are the autoab of Idiopathic Thrombocytopenic Purpura?

A

Anti-platelet Abs

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9
Q

What is/are the autoab of Autoimmune Hemolytic Anemia?

A

Anti-RBCs

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10
Q

What is/are the autoab of Primary Biliary Cirrhosis?

A

Anti-mitochondrial Abs

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11
Q

What is/are the autoab of Chronic Active Hepatitis?

A

Anti-smooth muscle Abs

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12
Q

What is/are the autoab of Crohn’s Disease?

A

p-ANCA 10-30% (Perinuclearantineutrophil cytoplasmic Ab)

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13
Q

What is/are the autoab of Primary Sclerosing Cholangitis?

A

p-ANCA

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14
Q

What is/are the autoab of Wegener’s Granulomatosis?

A

c-ANCA (Antineutrophil cytoplasmic)

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15
Q

What is/are the autoab of Multiple Sclerosis?

A

Anti-myelin sheath Abs

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16
Q

What is/are the autoab of Myasthenia Gravis?

A

Anti-acetylcholine receptor

17
Q

What is/are the autoab of DM type 1?

A

Anti-insulin Abs
Anti beta-islet cells
Anti-glutamic acid decarboxylase

18
Q

What is/are the autoab of Addison’s Disease?

A

Anti-adrenal cells

19
Q

What is/are the autoab of Pernicious Anemia?

A

Anti-parietal cells
Anti-intrinsic factor

20
Q

What is/are the autoab of Grave’s Disease?

A

Anti-TSH receptor

21
Q

What is/are the autoab of Hashimoto’s Thyroiditis?

A

Anti-thyroid peroxidase
Anti-thyroglobulin
Anti-microsomal

Immunoserology (20 decks)

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