FANA Flashcards

1
Q

A test used to RULE OUT SLE

A

FANA

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2
Q

Homogenous (Solid, Diffuse) pattern indicates the presence of what antibody?

A

Anti-DNP

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3
Q

Peripheral, Ring, membranous, Shaggy, Thread pattern indicates the presence of what antibody?

A

Anti-dsDNA

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4
Q

What is the most specific Ab in SLE?

A

Anti-dsDNA

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5
Q

HOMOGENOUS PATTERN (SOLID, DIFFUSE)

A

RHEUMATOID DISORDERS

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6
Q

PERIPHERAL, RING, MEMBRANOUS, SHAGGY, THREAD

A

SLE

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7
Q

SPECKLED, MOTTLED, PEPPER-DOT Antibodies?

A

Anti-ENA
Anti-Sm
Anti-RNP

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8
Q

Anti-Smith is indicative of what disease?

A

SLE

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9
Q

Anti-RNP is indicative of what disease?

A

MTCD, SLE, RA

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10
Q

What follow-up test for FANA that demonstrates a Speckled pattern?

A

Ouchterlony Double Diffusion

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11
Q

Another word for Speckled pattern?

A

Pepper-dot

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12
Q

Nucleolar pattern in FANA demonstrates the of what presence of Ab?

A

Nucleolar RNA Antibodies

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13
Q

Nucleolar pattern is indicATIVE OF WHAT DISEASE?

A

SCLERODERMA

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14
Q

Anti-Centromere Antibody indicates ….

A

CREST Syndrome

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15
Q

Meaning of CREST SYNDROME

A

C - CALCINOSIS
R - REYNAUD’S PHENOMENON
E - ESOPHANGEAL DISFUNCTION
S - SCLERODACTYLY
T - TELANGIECTASIA

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16
Q

What substrate is used for the anti-dsDNA test?

A

Crithidia Lucilia

17
Q

Crithidia Lucilia tests?

A

RIA, Indirect Immunofluorescence, ELISA

18
Q

What is the positive result for Crithidia Lucilia test?

A

Fluorescence of kinetoplast