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PMLS 1 > Immunology and Serology > Flashcards

Immunology and Serology Flashcards

1
Q

16th Century – Powdered smallpox crusts were inserted with a pin into the skin.

True or False

A

False (15th)

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2
Q

Using Cowpox lesions, he discovered
“cross-immunity”

CHOICES:
Elie Metchnikoff, Edward Jenner, Louis Pasteur

A

Edward Jenner

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3
Q

Father of Immunology

CHOICES:
Elie Metchnikoff, Edward Jenner, Louis Pasteur

A

Louis Pasteur

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4
Q

Cellular Theory of Immunity through Phagocytosis

CHOICES:
Elie Metchnikoff, Edward Jenner, Louis Pasteur

A

Elie Metchnikoff

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5
Q

The study of a host’s reactions when foreign substances are introduced into the body.

A

Immunology

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6
Q

The study of the ways the immune system can be advantageously manipulated to protect against or treat disease.

A

Immunology

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7
Q

The study of molecules, cells, organs and systems responsible for the recognition and disposal of foreign (non-self) material

A

Immunology

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8
Q

A branch of immunology that focuses on

the laboratory detection and measurement of antigens and antibodies.

A

Serology

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9
Q

Any foreign substance that

induces an immune response.

A

Antigen

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10
Q

The primary function is to
protect against microorganisms
and toxins.

A

Antibody

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11
Q

Antigen is a protein (Immunoglobulin)
produced by Plasma Cells to
neutralize antigens.

True or False

A

False (Antibody)

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12
Q

What line of defense is Adaptive Immunity?

A

third line

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13
Q

What line of defense is unbroken skin?

A

first line

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14
Q

What line of defense is sebum?

A

first line

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15
Q

What line of defense is natural immunity?

A

second line

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16
Q

What line of defense is normal flora?

A

first line

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17
Q

What line of defense is mast cell, neutrophil, and macrophage?

A

second line

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18
Q

What line of defense is T cells and B cells?

A

third line

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19
Q

What line of defense is plasma cells?

A

third line

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20
Q

What line of defense is mucous membranes?

A

first line

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21
Q

active immunity produces antibody and long responses

True or False

A

True

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22
Q

The type of artificial passive immunity is vaccination

True or False

A

False (active)

23
Q

A natural way to have an active immunity is through an infection

True or False

A

True

24
Q

Through infusion or serum/plasma, artificial passive immunity is achieved

True or False

A

True

25
Q

An immuno-biological substance designed to produce specific protection against a given disease.

A

Vaccine

26
Q

A vaccine contains antibody

True or False

A

False (antigen)

27
Q

A vaccine is “antigenic” but not “pathogenic”.

True or False

A

True

28
Q

What type of vaccine is the Hepatitis B vaccine?

CHOICES:
Live attenuated vaccine, Toxoid, cellular fraction vaccine, Live vaccine, killed inactivated vaccine, Recombinant Vaccine

A

Recombinant Vaccine

29
Q

What type of vaccine is Diptheria and tetanus?

CHOICES:
Live attenuated vaccine, Toxoid, cellular fraction vaccine, Live vaccine, killed inactivated vaccine, Recombinant Vaccine

A

Toxoid

30
Q

What type of vaccine is the smallpox vaccine?

CHOICES:
Live attenuated vaccine, Toxoid, cellular fraction vaccine, Live vaccine, killed inactivated vaccine, Recombinant Vaccine

A

Live vaccine

31
Q

What type of vaccine are typhoid, cholera, and rabies?

CHOICES:
Live attenuated vaccine, Toxoid, cellular fraction vaccine, Live vaccine, killed inactivated vaccine, Recombinant Vaccine

A

killed inactivated vaccine

32
Q

What type of vaccine is meningococcal polysaccharide vaccine?

CHOICES:
Live attenuated vaccine, Toxoid, cellular fraction vaccine, Live vaccine, killed inactivated vaccine, Recombinant Vaccine

A

cellular fraction vaccine

33
Q

What type of vaccine are plague, MMR, and influenza

CHOICES:
Live attenuated vaccine, Toxoid, cellular fraction vaccine, Live vaccine, killed inactivated vaccine, Recombinant Vaccine

A

Live attenuated vaccine

34
Q

Most vaccines are deep subcutaneous or intramuscular route

True or False

A

True

35
Q

the clumping together of antigen bearing cells, microorganisms or particles in the presence of specific antibodies.

A

Agglutination

36
Q

hemagglutination - RBC
coagglutination - Bacterial cells

True or False

A

True

37
Q

One Antibody attaches to the antigenic site (epitope) and not visible

A

Sensitization

38
Q

Sensitized particles adhere to one another forming a “lattice”.

A

Lattice Formation

39
Q

what kind of agglutination

• Antigen is found naturally on particle
• Blood Grouping: ABO
• Bacterial Serotyping: Salmonella, Tularemia,
Rickettsia, Typhoid
• Hemagglutination: Measles
A

Direct Agglutination

40
Q

what kind of agglutination

• Antigen is first bound to a particle to detect antibodies.
• Sample Particles include: - Sheep RBC’s
- Latex Particles
• Sample Tests:
• Anti-nuclear Antibodies (ANA)
• Rheumatoid Factor
• Group A Strep
• Viral Antibodies (CMV, Rubella, VZV)
A

Passive Agglutination

41
Q

If antigen is present in sample, it will bind with reagent antibodies.

True or False

A

True

42
Q

Soluble antigen and particle complete to attach to the limited antibody binding sites.

A

Agglutination Inhibition

43
Q

Refers to aggregation of test antigens with soluble antibodies to produce visible insoluble complexes.

A

Precipitation

44
Q

Midway reaction between agglutination and precipitation.

A

Flocculation

45
Q

specific test for typhoid fever

CHOICES:
C3c RID test, RPR, widal test, WIEL FELIX test, HIV Rapid test HLA, CRP, ASO, HBSAG rapid test

A

widal test

46
Q

non-specific tests for syphilis

CHOICES:
C3c RID test, RPR, widal test, WIEL FELIX test, HIV Rapid test HLA, CRP, ASO, HBSAG rapid test

A

RPR

47
Q

non-specific marker for inflammation

CHOICES:
C3c RID test, RPR, widal test, WIEL FELIX test, HIV Rapid test HLA, CRP, ASO, HBSAG rapid test

A

C3c RID test

48
Q

specific tests for syphilis

CHOICES:
C3c RID test, RPR, widal test, WIEL FELIX test, HIV Rapid test HLA, CRP, ASO, HBSAG rapid test

A

CRP

49
Q

diagnostic test for strptococcal infections

CHOICES:
C3c RID test, RPR, widal test, WIEL FELIX test, HIV Rapid test HLA, CRP, ASO, HBSAG rapid test

A

ASO

50
Q

non-specific test for rickettsial infections

CHOICES:
C3c RID test, RPR, widal test, WIEL FELIX test, HIV Rapid test HLA, CRP, ASO, HBSAG rapid test

A

WIEL FELIX test

51
Q

rapid qualitative test

CHOICES:
C3c RID test, RPR, widal test, WIEL FELIX test, HIV Rapid test HLA, CRP, ASO, HBSAG rapid test

A

HBSAG rapid test

52
Q

to determine paternity, compatibility in organ, tissue, and bone marrow

CHOICES:
C3c RID test, RPR, widal test, WIEL FELIX test, HIV Rapid test HLA, CRP, ASO, HBSAG rapid test

A

HLA

53
Q

fast screening tests that detects HIV 1 and 2

CHOICES:
C3c RID test, RPR, widal test, WIEL FELIX test, HIV Rapid test HLA, CRP, ASO, HBSAG rapid test

A

HIV Rapid test

PMLS 1 (23 decks)

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