Immunology and Serology Flashcards

1
Q

16th Century – Powdered smallpox crusts were inserted with a pin into the skin.

True or False

A

False (15th)

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2
Q

Using Cowpox lesions, he discovered
“cross-immunity”

CHOICES:
Elie Metchnikoff, Edward Jenner, Louis Pasteur

A

Edward Jenner

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3
Q

Father of Immunology

CHOICES:
Elie Metchnikoff, Edward Jenner, Louis Pasteur

A

Louis Pasteur

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4
Q

Cellular Theory of Immunity through Phagocytosis

CHOICES:
Elie Metchnikoff, Edward Jenner, Louis Pasteur

A

Elie Metchnikoff

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5
Q

The study of a host’s reactions when foreign substances are introduced into the body.

A

Immunology

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6
Q

The study of the ways the immune system can be advantageously manipulated to protect against or treat disease.

A

Immunology

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7
Q

The study of molecules, cells, organs and systems responsible for the recognition and disposal of foreign (non-self) material

A

Immunology

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8
Q

A branch of immunology that focuses on

the laboratory detection and measurement of antigens and antibodies.

A

Serology

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9
Q

Any foreign substance that

induces an immune response.

A

Antigen

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10
Q

The primary function is to
protect against microorganisms
and toxins.

A

Antibody

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11
Q

Antigen is a protein (Immunoglobulin)
produced by Plasma Cells to
neutralize antigens.

True or False

A

False (Antibody)

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12
Q

What line of defense is Adaptive Immunity?

A

third line

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13
Q

What line of defense is unbroken skin?

A

first line

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14
Q

What line of defense is sebum?

A

first line

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15
Q

What line of defense is natural immunity?

A

second line

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16
Q

What line of defense is normal flora?

A

first line

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17
Q

What line of defense is mast cell, neutrophil, and macrophage?

A

second line

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18
Q

What line of defense is T cells and B cells?

A

third line

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19
Q

What line of defense is plasma cells?

A

third line

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20
Q

What line of defense is mucous membranes?

A

first line

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21
Q

active immunity produces antibody and long responses

True or False

A

True

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22
Q

The type of artificial passive immunity is vaccination

True or False

A

False (active)

23
Q

A natural way to have an active immunity is through an infection

True or False

24
Q

Through infusion or serum/plasma, artificial passive immunity is achieved

True or False

25
An immuno-biological substance designed to produce specific protection against a given disease.
Vaccine
26
A vaccine contains antibody True or False
False (antigen)
27
A vaccine is “antigenic” but not “pathogenic”. True or False
True
28
What type of vaccine is the Hepatitis B vaccine? CHOICES: Live attenuated vaccine, Toxoid, cellular fraction vaccine, Live vaccine, killed inactivated vaccine, Recombinant Vaccine
Recombinant Vaccine
29
What type of vaccine is Diptheria and tetanus? CHOICES: Live attenuated vaccine, Toxoid, cellular fraction vaccine, Live vaccine, killed inactivated vaccine, Recombinant Vaccine
Toxoid
30
What type of vaccine is the smallpox vaccine? CHOICES: Live attenuated vaccine, Toxoid, cellular fraction vaccine, Live vaccine, killed inactivated vaccine, Recombinant Vaccine
Live vaccine
31
What type of vaccine are typhoid, cholera, and rabies? CHOICES: Live attenuated vaccine, Toxoid, cellular fraction vaccine, Live vaccine, killed inactivated vaccine, Recombinant Vaccine
killed inactivated vaccine
32
What type of vaccine is meningococcal polysaccharide vaccine? CHOICES: Live attenuated vaccine, Toxoid, cellular fraction vaccine, Live vaccine, killed inactivated vaccine, Recombinant Vaccine
cellular fraction vaccine
33
What type of vaccine are plague, MMR, and influenza CHOICES: Live attenuated vaccine, Toxoid, cellular fraction vaccine, Live vaccine, killed inactivated vaccine, Recombinant Vaccine
Live attenuated vaccine
34
Most vaccines are deep subcutaneous or intramuscular route True or False
True
35
the clumping together of antigen bearing cells, microorganisms or particles in the presence of specific antibodies.
Agglutination
36
hemagglutination - RBC coagglutination - Bacterial cells True or False
True
37
One Antibody attaches to the antigenic site (epitope) and not visible
Sensitization
38
Sensitized particles adhere to one another forming a “lattice”.
Lattice Formation
39
what kind of agglutination ``` • Antigen is found naturally on particle • Blood Grouping: ABO • Bacterial Serotyping: Salmonella, Tularemia, Rickettsia, Typhoid • Hemagglutination: Measles ```
Direct Agglutination
40
what kind of agglutination ``` • Antigen is first bound to a particle to detect antibodies. • Sample Particles include: - Sheep RBC’s - Latex Particles • Sample Tests: • Anti-nuclear Antibodies (ANA) • Rheumatoid Factor • Group A Strep • Viral Antibodies (CMV, Rubella, VZV) ```
Passive Agglutination
41
If antigen is present in sample, it will bind with reagent antibodies. True or False
True
42
Soluble antigen and particle complete to attach to the limited antibody binding sites.
Agglutination Inhibition
43
Refers to aggregation of test antigens with soluble antibodies to produce visible insoluble complexes.
Precipitation
44
Midway reaction between agglutination and precipitation.
Flocculation
45
specific test for typhoid fever CHOICES: C3c RID test, RPR, widal test, WIEL FELIX test, HIV Rapid test HLA, CRP, ASO, HBSAG rapid test
widal test
46
non-specific tests for syphilis CHOICES: C3c RID test, RPR, widal test, WIEL FELIX test, HIV Rapid test HLA, CRP, ASO, HBSAG rapid test
RPR
47
non-specific marker for inflammation CHOICES: C3c RID test, RPR, widal test, WIEL FELIX test, HIV Rapid test HLA, CRP, ASO, HBSAG rapid test
C3c RID test
48
specific tests for syphilis CHOICES: C3c RID test, RPR, widal test, WIEL FELIX test, HIV Rapid test HLA, CRP, ASO, HBSAG rapid test
CRP
49
diagnostic test for strptococcal infections CHOICES: C3c RID test, RPR, widal test, WIEL FELIX test, HIV Rapid test HLA, CRP, ASO, HBSAG rapid test
ASO
50
non-specific test for rickettsial infections CHOICES: C3c RID test, RPR, widal test, WIEL FELIX test, HIV Rapid test HLA, CRP, ASO, HBSAG rapid test
WIEL FELIX test
51
rapid qualitative test CHOICES: C3c RID test, RPR, widal test, WIEL FELIX test, HIV Rapid test HLA, CRP, ASO, HBSAG rapid test
HBSAG rapid test
52
to determine paternity, compatibility in organ, tissue, and bone marrow CHOICES: C3c RID test, RPR, widal test, WIEL FELIX test, HIV Rapid test HLA, CRP, ASO, HBSAG rapid test
HLA
53
fast screening tests that detects HIV 1 and 2 CHOICES: C3c RID test, RPR, widal test, WIEL FELIX test, HIV Rapid test HLA, CRP, ASO, HBSAG rapid test
HIV Rapid test