Hematology Flashcards
Scientific study of blood and its components
Hematology
Produced in the bone marrow by stem cells
White blood cells and Red blood cells
Consist of hemoglobin, the gas transporting protein molecule that gives its red color
Red blood cells
defend the body against infection
White blood cells
Conditions associated: anemia and polycythemia
Red blood cells
kills parasites and activate allergic response
eosinophils
most numerous and protects the body from infection by killing and ingesting bacteria, fungi, etc.
neutrophils
involved in allergic response
basophils
composed of T cells, B cells, and NK cells; responsible for adaptive immunity
Lymphocytes
ingest bacteria, foreign bodies; commonly increased in convalescent phase or chronic phase of infection
Monocytes
A high WBC count may be seen in the ff:
- Viral infection
- Congenital disorders characterized by diminished bone marrow function
- Cancer
- Autoimmune diseases
- Drugs
- Hypersplenism
- Parasitic infection
- Vitamin deficiencies
True or False
False (Low)
A high WBC count is caused by one of the following reasons:
- Infection
- Allergy
- Reaction to a drug
- Disease of bone marrow
- Immune system disorder that increases wbc production - Severe emotional or physical stress
- Strenuous exercise
True or False
True
adhere to the walls of the blood vessels to plug
ruptures, thereby preventing the release of blood
Platelets
Release chemical that cause clots to form in the blood
Platelets
A low platelet count may be a result of:
- Conditions in which platelets are consumed/ used up
- Short life span
- dengue
True or False
True
A high Platelet count is usually a result of an existing condition such as:
- Cancer
- Chronic kidney failure
- Anemia (IDA or HA)
- Inflammatory conditions
- Infectious disease
- Dengue
- Splenectomy
- Use of birth control pills
- Vitamin B12 or Folate deficiency
True or False
False (dengue results in low count of platelet)
It involved in secondary hemostasis; used to stabilized clots
Clotting factors
Types of Clotting factors:
Fibrinogen (Factor I) Prothrombin (Factor II) Thromboplastin (Factor III) Calcium (Factor IV) Proaccelerin or Labile Factor (Factor V) Stable Factor (Factor VII) Christmas Factor (Factor VIII) Antihemophilic Factor(Factor IX) Stuart - Power Factor (Factor X) Plasma Thrombin antecedent (Factor XI) Hegman Factor (Factor XII) Fibrin Stabilizing Factor (Factor XIII).
True or False
False [Antihemophilic Factor (Factor VIII) Christmas Factor (Factor IX)]
Laboratory analysis includes:
Mean corpuscular hemoglobin (MCH), RBC count, CT/BT, Erythrocyte sedimentation rate
True or False
True
Reticulocyte count is the same with WBC differential count and RBC count
True or False
False (no)
_______ tube used to evaluate bleeding tendencies
Sodium citrate
commonly used tube in hematological analysis; inverted 8x.
EDTA (Ethylenediametetraacetic acid)
production of blood
hematopoiesis
production of RBC
erythropoiesis
abnormal wbc count may indicate?
leukemia
elevated hematocrit %
polycythemia
