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PMLS 1 > Basic Concepts on Laboratory Biosafety and Biosecurity > Flashcards

Basic Concepts on Laboratory Biosafety and Biosecurity Flashcards

1
Q

Richard Nixon ordered the origins of biosafety during the Cold War. True or False.

A

False (Franklin Roosevelt)

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2
Q

__________ was designated a permanent installation for biological research and development.

A

Camp Detrick

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3
Q

He engaged some of Camp Detrick’s leading scientists about the nature of
their work and developed specific technical solutions such as Class III safety cabinets and laminar flow hoods to address specific risks.

A

Newell A. Johnson

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4
Q

He described the use of mechanical pipettors to
prevent laboratory-acquired infections in 1907
and 1908

A

Arnold Wedum

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5
Q

early progenitors to the nearly ubiquitous engineered control now known as the ___________ , were also first documented outside of the US biological weapons program.

A

biological safety cabinet

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6
Q

In 1909, a pharmaceutical company in Pennsylvania developed a ventilated cabinet to prevent infection from _____________.

A

Mycobacterium tuberculosis

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7
Q

At the height of increasing mortality and morbidity due to _______ in 1967, WHO aggressively pursued the eradication of the Virus.

A

smallpox

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8
Q

World Health Assembly consolidated the

remaining virus stocks into two locations

A

CDC and SRCVB

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9
Q

The technical means of mitigating the
risk of accidental infection from or release of agents in the laboratory setting as well as the community and environment it is situated in.

A

Biosafety levels

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10
Q

He was recognized as one Of the pioneers of
biosafety that provided the foundation for evaluating the risks of handling infectious microorganisms and for recognizing biological hazards and developing practices, equipment, and facility safeguards for their control.

A

Arnold Wedum

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11
Q

To monitor the transfer of a select list of
biological agents from one facility to
another.

A

Select Agent Regulations

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12
Q

Anthrax attacks of 2001, also known as ________

A

Amerithrax

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13
Q

Materials that pose the greatest risk of deliberate misuse, and the remaining select agents.

A

Tier 1 Agents

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14
Q

Similar in scope with the US regulations
but with more severe penalties for noncompliance

CHOICES:
Singapore’s Biological Agents and Toxins Act, Japan - Infectious Disease Control Law, South Korea - Act on Prevention of Infectious Diseases in 2005, Comité Européen de Normalisation (CEN)

A

Singapore’s Biological Agents and Toxins Act

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15
Q

Amended to require institutions that work with listed “highly dangerous pathogens” to implement laboratory biosafety and biosecurity requirements to prevent the loss, theft, diversion, release, or misuse of these agents.

CHOICES:
Singapore’s Biological Agents and Toxins Act, Japan - Infectious Disease Control Law, South Korea - Act on Prevention of Infectious Diseases in 2005, Comité Européen de Normalisation (CEN)

A

South Korea - Act on Prevention of Infectious Diseases in 2005

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16
Q

Established four schedules of select agents that are subject to different reporting and handling requirement for possession, transport and other activities

CHOICES:
Singapore’s Biological Agents and Toxins Act, Japan - Infectious Disease Control Law, South Korea - Act on Prevention of Infectious Diseases in 2005, Comité Européen de Normalisation (CEN)

A

Japan - Infectious Disease Control Law

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17
Q

Intended to maintain a biorisk management system among diverse organizations and set out performance-based requirements with the exclusion of guidance for implementing a national biosafety system

CHOICES:
Singapore’s Biological Agents and Toxins Act, Japan - Infectious Disease Control Law, South Korea - Act on Prevention of Infectious Diseases in 2005, Comité Européen de Normalisation (CEN)

A

Comité Européen de Normalisation (CEN)

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18
Q

To address concerns on biosafety guidance for research and health laboratories, issues on risk assessment and guidance to commission and certify laboratories and includes information on the different levels of containment laboratories (Biosafety levels 1-4)

A

Laboratory Biosafety Manual - 3rd edition

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19
Q

To ensure “an adequate level of protection in the field of safe transfer, handling, and use of living modified organisms (LMOS) resulting from modern biotechnology.”

CHOICES:
National Biosafety Framework (NBF), Cartagena Protocol on Biosafety (CPB), DOH Administrative Order No. 2007- 0027, National Committee on Biosafety of the Philippines (NCBP)

A

Cartagena Protocol on Biosafety (CPB)

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20
Q

Established under E.O. 430 series of 1990 that has the procedures for evaluation of proposals with biosafety concerns

CHOICES:
National Biosafety Framework (NBF), Cartagena Protocol on Biosafety (CPB), DOH Administrative Order No. 2007- 0027, National Committee on Biosafety of the Philippines (NCBP)

A

National Committee on Biosafety of the Philippines (NCBP)

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21
Q

Combination of policy, legal, administrative, and technical instruments developed to attain the objective of the Cartagena Protocol on Biosafety which the Philippines signed on May 24, 2000

CHOICES:
National Biosafety Framework (NBF), Cartagena Protocol on Biosafety (CPB), DOH Administrative Order No. 2007- 0027, National Committee on Biosafety of the Philippines (NCBP)

A

National Biosafety Framework (NBF)

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22
Q

It requires clinical laboratories to ensure policy guidelines on laboratory biosafety and biosecurity

CHOICES:
National Biosafety Framework (NBF), Cartagena Protocol on Biosafety (CPB), DOH Administrative Order No. 2007- 0027, National Committee on Biosafety of the Philippines (NCBP)

A

DOH Administrative Order No. 2007- 0027

23
Q

Promotes biosafety as a “scientific discipline” and provides guidance to its members on the
regulatory regime present in North America

CHOICES:
Asia-Pacific Biosafety Association (A-PBA), Philippine Biosafety and Biosecurity Association (PhBBA), American biological safety association (ABSA), Biological Risk Association Philippines (BRAP), European Biological Safety Association (EBSA)

A

American biological safety association (ABSA)

24
Q

Acts as a professional society for biosafety
professionals in the Asia-Pacific region

CHOICES:
Asia-Pacific Biosafety Association (A-PBA), Philippine Biosafety and Biosecurity Association (PhBBA), American biological safety association (ABSA), Biological Risk Association Philippines (BRAP), European Biological Safety Association (EBSA)

A

Asia-Pacific Biosafety Association (A-PBA)

25
Q

A long-term goal = assist the DA and DOH in their efforts to create a national policy and implement plan for laboratory biosafety and biosecurity.

CHOICES:
Asia-Pacific Biosafety Association (A-PBA), Philippine Biosafety and Biosecurity Association (PhBBA), American biological safety association (ABSA), Biological Risk Association Philippines (BRAP), European Biological Safety Association (EBSA)

A

Philippine Biosafety and Biosecurity Association (PhBBA)

26
Q

Aims to provide a forum for discussions and
debates on issues of concern and to represent
those working in the field of biosafety.

CHOICES:
Asia-Pacific Biosafety Association (A-PBA), Philippine Biosafety and Biosecurity Association (PhBBA), American biological safety association (ABSA), Biological Risk Association Philippines (BRAP), European Biological Safety Association (EBSA)

A

European Biological Safety Association (EBSA)

27
Q

Launched numerous activities in cooperation
and collaboration on a national and international scale in the promotion of biosafety, biosecurity, and biorisk management as scientific disciplines.

CHOICES:
Asia-Pacific Biosafety Association (A-PBA), Philippine Biosafety and Biosecurity Association (PhBBA), American biological safety association (ABSA), Biological Risk Association Philippines (BRAP), European Biological Safety Association (EBSA)

A

Biological Risk Association Philippines (BRAP)

28
Q

Containment principles, technologies and

practices that are implemented to prevent unintentional exposure to pathogens and toxins, or their accidental release.

29
Q

The protection, control and accountability for valuable biological materials within laboratories in order to prevent their unauthorized access, loss, theft, misuse, diversion, or intentional release

A

Biosecurity

30
Q

Protects the people from germs

31
Q

Protects the germs from people

A

Biosecurity

32
Q

He created the biohazard symbpol used

in labeling biological materials carrying significant health risks.

A

Charles Baldwin

33
Q

It includes microorganisms that are unlikely to cause human or animal disease

A

Risk group 1

34
Q

It includes microorganisms that are known to cause serious diseases to humans or animals and may present a significant risk to laboratory workers.

A

Risk group 3

35
Q

It includes microorganisms that are unlikely to be a significant risk to laboratory workers and the community, livestock, or the environment

A

Risk group 2

36
Q

Microorganisms that are known to produce Iife-threatening diseases to humans or animals.

A

Risk group 4

37
Q

Low individual and community risk

A

Risk group 1

38
Q

Could present a limited to moderate risk if these microorganisms spread in the community or the environment

A

Risk group 3

39
Q

It represents a significant risk to laboratory workers

A

Risk group 4

40
Q

Laboratory exposure may cause infection, however, effective treatment and preventive measures are available

A

Risk group 2

41
Q

____ categorized laboratories into four biosafety levels

42
Q

Most appropriate among undergraduate and secondary educational training and teaching laboratories that require basic laboratory safety practices, safety equipment, and facility design that requires basic level of containment

A

Biosafety Level 1 (BSL-l)

43
Q

Emphasis on primary and secondary barriers in the protection of the personnel, the community, and the environment from infectious aerosol exposure

A

Biosafety Level 3 (BSL-3)

44
Q

Dangerous and exotic agents that pose high individual risks of life-threatening diseases that may be transmitted via the aerosol route

A

Biosafety Level 4 (BSL-4)

45
Q

Observes practices, equipment, and facility design that are applicable to clinical, diagnostic, and teaching laboratories consequently observing good microbiological techniques

A

Biosafety Level 2 (BSL-2)

46
Q

Hepatitis B virus

A

Biosafety Level 2 (BSL-2)

47
Q

Marburg or the Crimean-Congo hemorrhagic fever

A

Biosafety Level 4 (BSL-4)

48
Q

Coxiella

A

Biosafety Level 3 (BSL-3)

49
Q

HIV

A

Biosafety Level 2 (BSL-2)

50
Q

Bacillus subtilis

A

Biosafety Level 1 (BSL-l)

51
Q

St. Louis encephalitis virus

A

Biosafety Level 3 (BSL-3)

52
Q

Naegleria gruberi

A

Biosafety Level 1 (BSL-l)

53
Q

infectious canine hepatitis Virus

A

Biosafety Level 1 (BSL-l)

54
Q

salmonellae

A

Biosafety Level 2 (BSL-2)

PMLS 1 (23 decks)

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