ID DOC, Renal adj, Special Req, Key Counseling Flashcards
DOC for MSSA
Diclox, naf, oxacillin Cefazolin, cephalexin (1st and 2nd gen) Amox/clav, ampicillin/sulbactam Doxycycline, minocycline SMX/TMP
DOC for CA-MRSA
SMX/TMP
Doxycycline, minocycline
Clindamycin
Linezolid
DOC for Severe skin and soft tissue infections requiring IV treatment
Need to cover for MRSA and strep
Vanc
linezolid
Daptomycin
Ceftaroline
DOC for nosocomial MRSA
Vanc
Linezolid
Daptomycin (not pneumonia)
DOC for VRE (e. faecalis)
Pen G or ampicillin
Linezolid
Daptomycin
Cystitis only: nitrofurantoin, fosfomycin, doxycycline
DOC for VRE (e. faecium)
Dapto
Linezolid
Cystitis only nitrofurantoin, fosfomycin, doxycycline
DOC for pseudomonas
Pip/tazo Cefepime Ceftazidime Ceftazidime/avibactam Ceftolozane/tazobactam Carbapenems (except erta) Ciprofloxacin, levofloxacin Aztreonam Aminoglycosides Colistimethate, polymyxin B
DOC for ESBL GNR
E. coli, K. pneumoniae, P. mirabilis
Carbapenems
Ceftolozanetazobatam
Ceftazidime/avibactam
DOC for carbapenem-resistant GNR (CRE)
Ceftazidime/Avibactam
Colistimethate, polymyxin B
DOC for acinetobacter baumannii
Carbapenems (except ertapenem) Ampicillin/sulbactam Minocycline/tigecycline Quinolones bactrim colistin
DOC for HNPEK
beta-lactam/beta-lactamase inhibitor Amoxicillin Cephalosporins Carbapenems Bactrim AG FQ
DOC for Bacteroides fragilis
Metronidazole
Beta-lactam/beta-lactamase inhibitor
Cefotetan, fefoxitin
Carbapenems
DOC for C. diff
Vanc (ORAL ONLY)
Fidazomicin
Metronidazole
Rifaximin
DOC for Atypical organisms
Azithromycin
Doxycycline
FQ
What abx do not need renally adjusted?
Diclox and nafcillin Ceftriaxone Clindamycin Doxycycline Azithromycin and erythromycin Metronidazole Moxifloxacin Linezolid ORAL vanc
What medications should be taken on an EMPTY stomach?
ampicillin oral cap and susp, ceftibuten susp, levofloxacin oral soln, PCN VK, rifampin, isoniazid, itraconazole soln, voriconazole
What abx are 1:1 IV:PO dosing?
Levofloxacin, moxifloxacin Doxycycline, minocycline Bactrim Linezolid Metronidazole Fluconazole, isavuconazonium, posaconazole, voriconazole
What abx need to be protected from light during administration
Doxycycline
Micafungin
Pentamidine
What abx are compatible with dextrose only?
Dalbavancin, oritavancin Pentamidine Quinupristin/dalfopristin bactrim Amphotericin B
What abx are compatible with saline only?
Ampicillin
Amp/sulbactam
Ertapenem
Daptomycin
What abx are compatable with NS/LR only
Caspofungin and daptomycin
Key counseling points for
beta-lactam abx
can cause seizures with accumulation
Key counseling points for
FQ
Can cause CNS effects (seizures), hypo/hyperglycemia, peripheral neuropathy, photosensitivity, QT prolongation, tendon inflammation
Avoid in pregnancy, breastfeeding and children
Drug interactions due to binding
Key counseling points for
Macrolides
Can cause GI upset, QT prolongation
Key counseling points for
tetracyclines
Avoid in pregnancy, breastfeeding, and children <8
Drug interactions due to binding
Photosensitivity
Doxycycline: take with full glass of water and stay upright for 30 minutes
Key counseling points for
bactrim
Avoid in pregnancy/breastfeeding
Can cause photosensitivity and crystals in urine (take with lots of water!)
Key counseling points for
metronidazole
Do not use any alcohol products
Can cause nausea and metallic taste
Key counseling points for
Nitrofurantoin
Take with food to decrease nausea
Can cause nausea and brown urine (harmless)
