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NAPLEX Review > ID DOC, Renal adj, Special Req, Key Counseling > Flashcards

ID DOC, Renal adj, Special Req, Key Counseling Flashcards

1
Q

DOC for MSSA

A 
Diclox, naf, oxacillin
Cefazolin, cephalexin (1st and 2nd gen)
Amox/clav, ampicillin/sulbactam
Doxycycline, minocycline
SMX/TMP
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2
Q

DOC for CA-MRSA

A

SMX/TMP
Doxycycline, minocycline
Clindamycin
Linezolid

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3
Q

DOC for Severe skin and soft tissue infections requiring IV treatment

A

Need to cover for MRSA and strep

Vanc
linezolid
Daptomycin
Ceftaroline

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4
Q

DOC for nosocomial MRSA

A

Vanc
Linezolid
Daptomycin (not pneumonia)

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5
Q

DOC for VRE (e. faecalis)

A

Pen G or ampicillin
Linezolid
Daptomycin
Cystitis only: nitrofurantoin, fosfomycin, doxycycline

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6
Q

DOC for VRE (e. faecium)

A

Dapto
Linezolid
Cystitis only nitrofurantoin, fosfomycin, doxycycline

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7
Q

DOC for pseudomonas

A 
Pip/tazo
Cefepime
Ceftazidime
Ceftazidime/avibactam
Ceftolozane/tazobactam
Carbapenems (except erta)
Ciprofloxacin, levofloxacin
Aztreonam
Aminoglycosides
Colistimethate, polymyxin B
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8
Q

DOC for ESBL GNR

E. coli, K. pneumoniae, P. mirabilis

A

Carbapenems
Ceftolozanetazobatam
Ceftazidime/avibactam

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9
Q

DOC for carbapenem-resistant GNR (CRE)

A

Ceftazidime/Avibactam

Colistimethate, polymyxin B

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10
Q

DOC for acinetobacter baumannii

A 
Carbapenems (except ertapenem)
Ampicillin/sulbactam
Minocycline/tigecycline
Quinolones
bactrim
colistin
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11
Q

DOC for HNPEK

A 
beta-lactam/beta-lactamase inhibitor
Amoxicillin
Cephalosporins
Carbapenems
Bactrim
AG
FQ
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12
Q

DOC for Bacteroides fragilis

A

Metronidazole
Beta-lactam/beta-lactamase inhibitor
Cefotetan, fefoxitin
Carbapenems

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13
Q

DOC for C. diff

A

Vanc (ORAL ONLY)
Fidazomicin
Metronidazole
Rifaximin

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14
Q

DOC for Atypical organisms

A

Azithromycin
Doxycycline
FQ

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15
Q

What abx do not need renally adjusted?

A 
Diclox and nafcillin
Ceftriaxone
Clindamycin
Doxycycline
Azithromycin and erythromycin
Metronidazole
Moxifloxacin
Linezolid
ORAL vanc
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16
Q

What medications should be taken on an EMPTY stomach?

A

ampicillin oral cap and susp, ceftibuten susp, levofloxacin oral soln, PCN VK, rifampin, isoniazid, itraconazole soln, voriconazole

17
Q

What abx are 1:1 IV:PO dosing?

A 
Levofloxacin, moxifloxacin
Doxycycline, minocycline
Bactrim
Linezolid
Metronidazole
Fluconazole, isavuconazonium, posaconazole, voriconazole
18
Q

What abx need to be protected from light during administration

A

Doxycycline
Micafungin
Pentamidine

19
Q

What abx are compatible with dextrose only?

A 
Dalbavancin, oritavancin
Pentamidine
Quinupristin/dalfopristin
bactrim
Amphotericin B
20
Q

What abx are compatible with saline only?

A

Ampicillin
Amp/sulbactam
Ertapenem
Daptomycin

21
Q

What abx are compatable with NS/LR only

A

Caspofungin and daptomycin

22
Q

Key counseling points for

beta-lactam abx

A

can cause seizures with accumulation

23
Q

Key counseling points for

FQ

A

Can cause CNS effects (seizures), hypo/hyperglycemia, peripheral neuropathy, photosensitivity, QT prolongation, tendon inflammation
Avoid in pregnancy, breastfeeding and children
Drug interactions due to binding

24
Q

Key counseling points for

Macrolides

A

Can cause GI upset, QT prolongation

25
Q

Key counseling points for

tetracyclines

A

Avoid in pregnancy, breastfeeding, and children <8
Drug interactions due to binding
Photosensitivity

Doxycycline: take with full glass of water and stay upright for 30 minutes

26
Q

Key counseling points for

bactrim

A

Avoid in pregnancy/breastfeeding

Can cause photosensitivity and crystals in urine (take with lots of water!)

27
Q

Key counseling points for

metronidazole

A

Do not use any alcohol products

Can cause nausea and metallic taste

28
Q

Key counseling points for

Nitrofurantoin

A

Take with food to decrease nausea

Can cause nausea and brown urine (harmless)

NAPLEX Review (79 decks)

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