ADHD Flashcards
What is the primary treatment for ADHD? Why?
Stimulant medications
They raise dopamine and norepinephrine levels
First line treatment for pre-school aged children (4-5) with ADHD
Parent training in behavior management and/or behavioral classroom intervention
First line treatment for patients aged 6 and up with ADHD
Medication
When to use atomoxetine (Strattera)
Non-stimulant that can be used when stimulants do not work well enough – can be first line if prescribers are concerned about the possibility of abuse by the patient or family
What drug formulations are beneficial in children
Capsule – can be sprinkled Chew tab ODT Patch Suspension
Stimulant medication BBW CI and warnings
BBW: High potential for abuse and dependence
CI: Do not use within 14 days of an MAOi d/t risk of HTN crisis
Warnings: Increased HR and BP, psychosis, seizures, loss of appetite, risk of serotonin syndrome
Stimulant MOA
Block reuptake of NE and DA
What medications are stimulants?
Methylphenidate Dexmethylphenidate Amphetamine Lisdexamfetamine Methamphetamine
Methylphenidate brand names
IR – Ritalin ER – Concerta ER – Ritalin LA ER suspension – Quillivant Patch – Daytrana
Methylphenidate SE, monitoring
SE: insomnia, decreased appetite, weight loss, HA, irritability
Monitoring: ECG prior to treatment; monitor BP and HR, height and weight in children
Which methylphenidate formulation can cause ghost tablets
Concerta
Dexmethylphenidate notes
Active isomer of methylphenidate
Amphetamine, dextroamphetamine combo (Adderall) BBW
Misuse can cause sudden death and serious CV events
Lisdexamfetamine (Vyvanse) formulations, notes
Formulations: capsule, chew tab
Notes: low abuse potential, prodrug composed of L-lysine
Methamphetamine brand name
Desoxyn
