I G Energy & Macronutrients (CHO, PRO, FAT) Flashcards
glycolysis vs. gluconeogenesis vs. glycogenesis vs. glycogenolysis**
- glycolysis = glucose –> pyruvate or pyruvic acid for use in Krebs cycle
- gluconeogenesis = conversion of NON-CHO sources into GLUCOSE (from GLYCEROL, AAs)
- glycogenesis = glucose –> glycogen or storage form
- glycogenolysis = glycogen (stored form) –> glucose
the brain uses _____ exclusively as an energy source; uses _____ during starvation**
- glucose = energy source
- ketone bodies = starvation
tissue stores of glucose
- GLYCOGEN - muscle and liver
- fat from adipose tissue
- cellular mass (protein stores)
what is gluconeogenesis?**
conversion of NON-CHO sources INTO GLUCOSE from GLYCEROL AND AMINO ACIDS
homeostasis
state of equilibrium of the internal environment of the body
enzymes are what type of compound?***
PROTEINS
enzymes
organic catalysts that control reactions
what are coenzymes?
enzyme activators; include some vitamins
what coenzymes are needed for energy production?**
1) pantothenic acid
2) thiamin (B1)
3) riboflavin (B2)
4) niacin (B3)
substrate
substrate = substance upon which an enzyme works
cofactor
assist enzymes, minerals
what are hormones?
secretions from endocrine glands, chemical messengers that trigger enzymes
what hormone regulates metabolism and the rate of oxidation?
THYROXINE - influences physical and mental growth
thyroxine stimulates what 2 processes?
liver glycogenolysis (glycogen –> glucose) and gluconeogenesis (creation of glucose from non-CHO sources) = raises blood sugar
anabolism
synthesis of a more complex substance
catabolism
breakdown, uses and releases energy; creates a constant energy deficit which must be supplied by food
3 components of total energy expenditure***
1) basal energy expenditure (BEE)
2) energy expended in physical activity
3) thermic effect of food (TEF)
basal energy expenditure
minimum amount of energy needed at rest in fasting (amount needed to carry out involuntary work of the body, activity of internal organs, internal temperature)
basal energy expenditure is affected by?**
- temperature (hot = 5-20% increase)
- caffeine
- alcohol
- nicotine (all increase 7-15%)
energy expended in physical activity is AKA?
activity thermogenesis
thermic effect of food
energy needed to digest, absorb, and assimilate nutrients (diet-induced thermogenesis or the calorigenic effect of food)
thermic effect of food is greater after what types of nutrients?**
greater after consumption of carbohydrate and protein than after fat
most variable part of total energy expenditure?
physical activity
what is the basal metabolic rate? when is it measured?
measured in morning when reclining, awake, relaxed, at normal body temperature, at least 12 hours after last meal, and several hours after strenuous activity
what does the BMR measure?
oxygen consumed
BMR is primarily affected by?
sex, age, body composition, endocrine glands (thyroid)
how does sex affect BMR?
women have 5-10% lower BMR than men
highest BMR is at what age?***
0-2 y/o
how does old age affect BMR?
less activity, less lean body mass and more body fat = lower BMR
what is PBI? what does it measure?***
protein bound iodine = measures activity of thyroid gland, therefore energy metabolism
associated hormones with PBI
thyroxine (T4) and triiodothyronine (T3)
relationship between PBI and BMR***
when PBI is elevated, BMR is elevated
when is BMR elevated?**
- GROWTH
- PREGNANCY
- LACTATION
- FEVER
- CA & HTN
how much does BMR rise with a fever?***
7% increase for each degree rise in temperature (98.6 is a normal temperature)
BMR can be increased by?
exercise
what is RMR?
resting metabolic rate: energy expenditure measured under similar conditions to BMR after a short rest and controlled intake of caffeine and alcohol
which is more frequently measured - BMR or RMR?***
RMR
what equation BEST predicts closest to indirect calorimetry? (within 10%)***
MSJ (Mifflin St. Jeor)
who should you use the MSJ equation with?***
NORMAL and OBESE individuals
what is the most PRACTICAL way of measuring ENERGY BALANCE?***
following changes in weight
direct calorimetry***
measures heat produced IN a respiration chamber
indirect calorimetry***
measures OXYGEN CONSUMED and CO2 excreted using a PORTABLE MACHINE
benefits of indirect calorimetry?***
PRACTICAL WAY of measuring which nutrients are being used for energy
indirect calorimetry is useful for?***
ATHLETE & CRITICALLY ILL
what is the respiratory quotient?
shows what type of fuel is being metabolized (CO2 expired/oxygen consumed)
RQ for CHO alone***
1
RQ for mixed intake**
0.85