Hypothalamus & Pituitary Gland Flashcards
what are the functions of the Hypothalamus?
The hypothalamus integrates functions that maintain chemical and temperature homeostasis. It functions with the limbic system and controls the release of hormones from the anterior and posterior pituitary. It synthesizes and releases hypophysiotropic hormones in the cell bodies of neurons located in the hypothalamus:
what are the two mechanisms exerted by the hypothalamus?
Neural (local circuits, afferent and efferent projections)
Neurohumoral (i.e., hormonal, vascular, neuroendocrine functions, neuroimmune influences)
what are the three sites of functional influence?
anterior pituitary
posterior pituitary
non pituitary
what are anterior pituitary influences?
Stress “Fight (aggressive behavior) or Flight (fear)” Sexual behavior and reproduction Growth Metabolism
what are the posterior pituitary influences?
Body fluid balance
Maternal behavior
what are the non-pituitary influences?
Temperature regulation Immune system regulation Circadian rhythm influences on hormonal fluctuations, sleep, etc. Appetite regulation Autonomic Nervous System
what are the afferent connections to the hypothalamus? functions?
the fornix - communicates from the hippocampus
medial forebrain - from the olfactory areas
stria terminalis - from the amygdala
peduncle - from the visceral afferent fibers
what are the efferent connections to the hypothalamus? functions?
dorsal longitudinal fasciculus - to parasympathetic nuclei
mamillotegmental tract - fibers to the tegmentum of the midbrain
mamillothalamic fasciculus to cingulate gyrus
Hypothalamic - hypophyseal tract communicates with pituitary gland
so we know that the mamillotegmental tract is part of the efferent connections to the hypothalamus, what is this pathway?
tegmentum of the midbrain - reticular formation - hypothalamus, cranial nerve nuclei, spinal cord
what is the pituitary gland divided into?
adenohypophysis and neurohypophysis
what is the adenohypophysis?
anterior pituitary containing the Pars tuberalis, Pars intermedia, Pars distalis
what is the neurohypophysis?
posterior pituitary containing infundibular stalk
where does the anterior and posterior pituitary glands sit?
the hypophyseal fossa in the sella turcica of the sphenoid bone
what supplies the anterior portion of the pituitary gland? posterior portion of the pituitary gland?
superior hypophyseal artery; inferior hypophyseal artery
this structure is characterized by sexual dimorphism involving hormonal influences on neuronal maturation? what hormone does this structure contain?
medial preoptic nucleus; gonadotropin-releasing hormone