Hyperkalaemia Flashcards
What is hyperkalaemia defined as?
Serum potassium concentration >5.5mmol/L.
What is classed as mild hyperkalaemia?
5.5 - 5.9 mmol/L
What is classed as moderate hyperkalaemia?
6.0 - 6.4 mmol/L
What is classed as severe hyperkalaemia?
≥ 6.5 mmol/L
Which drugs can cause hyperkalaemia?
ACE inhibitors
Angiotensin receptor blockers
Potassium sparing diuretics ( spironolactone)
NSAIDs
Heparin/low molecular weight heparin
Ciclosporin
High dose trimethoprim
What is a major problem with untreated hyperkalaemia?
May cause life-threatening arrhythmias
How can hyperkalaemia be diagnosed/ the severeity assessed ?
ECG
What is the first change seen on an ECG?
Peaked or Tall tented T-waves
What other ECG changes occur in hyperkalaemia?
loss of P waves
prolonged PR interval
broad QRS complexes
sinusoidal wave pattern
What is the initial treament of hyperkalaemia?
IV calcium gluconate
stabalisation of the cardiac membrane
What does IV calcium gluconate not do?
Lower serum potassium levels
How should the calcium gluconate be administered?
10ml of 10% calcium gluconate over 10 mins
What is the next step in the management of hyperkalaemia?
combined insulin/dextrose infusion
or
nebulised salbutamol
What is the function of insulin/dextrose/nebulised salbutamol?
Short-term shift in potassium from extracellular (ECF) to intracellular fluid (ICF)
compartment
What does insulin/dextrose/nebulised adrenaline not do?
Remove potassium from the body