Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Urinary > Glomerulonephritis > Flashcards

Glomerulonephritis Flashcards

1
Q

What is IgA nephropathy also known as?

A

Berger’s disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the commonest cause of glomerulonephritis worldwide?

A

IgA nephropathy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Which conditions are associated with IgA nephropathy?

A
  • alcoholic cirrhosis
  • coeliac disease/dermatitis herpetiformis
  • Henoch-Schonlein purpura
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

How does IgA nephropathy normally present?

A

Episodic haematuria
Sore throat
Young person

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is IgA nephropathy caused by?

A

Mesangial deposition of IgA immune complexes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What would you see on IgA nephropathy histology

A

Mesangial hypercellularity

Positive immunofluorescence for IgA & C3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

When does post-streptococcal glomerulonephritis occur?

A

1-3 weeks following an upper respiratory tract infection (URTI)
3-6 weeks following a skin infection.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What type of hypersensitivity reaction is post-streptococcal glomerulonephritis?

A

Type 3 hypersensitivity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Which type of syndrome is post-streptococcal glomerulonephritis?

A

Nephritic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What bacteria causes post-streptococcal glomerulonephritis?

A

Streptococcus pyogenes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is post-streptococcal glomerulonephritis caused by?

A

Immune complex (IgG, IgM and C3) deposition in the glomeruli.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Who is most commonly affected by post-streptococcal glomerulonephritis?

A

Young people

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

How does post-streptococcal glomerulonephritis present?

A 
Headache
Malaise
Visible haematuria
Proteinuria- this may result in oedema
Hypertension
Oliguria
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What might you find in the blood of someone with post-streptococcal glomerulonephritis?

A

Low C3

Raised ASO titre (Anti-streptolysin O antibodies)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What might you see with immunofluorescence in someone with post-streptococcal glomerulonephritis?

A

Granular or ‘starry sky’ appearance

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is another name for cresenteric glomerulonephritis?

A

Granulomatosis with polyangiitis

Wegner’s granulomatosis

17
Q

What is granulomatosis with polyangiitis?

A

Autoimmune condition associated with a necrotizing granulomatous vasculitis

18
Q

What does granulomatosis with polyangiitis affect?

A

Both the upper and lower respiratory tract as well as the kidneys.

19
Q

What upper respiratory tract symptoms do you get with granulomatosis with polyangiitis?

A

Epistaxis
Sinusitis
Nasal crusting

20
Q

What lower respiratory tract symptoms do you get with granulomatosis with polyangiitis?

A

Dyspnoea

Haemoptysis

21
Q

What additional symptoms do you get with granulomatosis with polyangiitis?

A 
Saddle-shape nose deformity
Vasculitic rash
Eye involvement (e.g. proptosis)
Cranial nerve lesions
Rapidly progressive glomerulonephritis
22
Q

What predisposes people with nephrotic syndrome to the development of venous thromboembolism?

A

Loss of antithrombin-III, proteins C and S and an associated rise in fibrinogen

Urinary (38 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions