Humoral Immunity

Question 1

Step one

Answer 1

When an antigen enters the bloodstream or tissue fluid there will be at least one B-cell that has an antibody on its surface that is complimentary that will attach to the antigen

Question 2

Step 2

Answer 2

The antigen enters the B-cell by endocytosis and then gets presented on the cell surface which is then called the antigen/receptor complex

Question 3

Step 3

Answer 3

At this point, the percentage antigen/receptor complex can also be bound by a T-helper cell. The T-helper cells and stimulates the specific B cells colonial selection to divide by mitosis to make many more identical B cells ( colonial expansion). Clonned B-cells, produce one type of antibody (monoclonal antibody) each clone becomes one of two cells.

Question 4

What are the two cells clonned B-cells become

Answer 4

1- plasma cells
2- B-memory cells

Question 5

What do plasma cells do?

Answer 5

-Fight off the primary infection
- In the life of the few days they produce up to 2000 antigens

Question 6

What do B-memory cells do?

Answer 6

-Circulate in the blood and are responsible for the secondary immune response
-can live for several years