Cell Mediated Response

Question 1

What are lymphocytes

Answer 1

White blood cells involved in a specific immune response categorised into T or B cells

Question 2

Where are T-cells produced

Answer 2

In the bone marrow and mature in the thymus

Question 3

Where are B-cells produced

Answer 3

-in the bone marrow and mature there

Question 4

Cell mediated response step by step

Answer 4

1-A phagocyte engulfs and try just a pathogen it presents the pathogen is antigens on the surface membrane
2-The T-helper cells have receptors in the surface and bind to the antigen on the antigen presenting cell
3-Once attached this activates the T-helper cells to divide by mitosis and make a large number of clones, clonal expansion

Question 5

The cloned T-helper cells differentiate forming 4 cells what are they?

Answer 5

1- memory cells
2-some stimulate phagocytes to engulf pathogens
3-activate cytosine t-cells (killer T-cells)
4-some remain as T-helper cells and stimulate specific B-cells to divide and secrete antibodies

Question 6

How do cytosine T-cells work

Answer 6

It releases a protein called Perofin which makes holes in the membrane of the target cell and makes it freely permeable and causes the cells to be destroyed most common in viral infections

Question 7

What type of cells do t-lymphocytes respond to

Answer 7

-Antigen presenting phagocytes
-cells transplanted from a donor
-Cancer cells with altered surface antigens
-Virally infected cells are presenting same viral antigens on the membrane