HIV/AIDS Flashcards
Exam 2
OVERVIEW — HIV/AIDS
HIV disease- What is it caused by?
Caused by the human immunodeficiency virus (HIV)
OVERVIEW — HIV/AIDS
HIV disease- How does it range?
Several stages ranging from acute infection to death
OVERVIEW — HIV/AIDS:
For HIV-infected individual who does not receive treatment, what can occur?
Infection to death is nearly 12 years
HUMAN IMMUNODEFICIENCY VIRUS (HIV):
Epidemiology: How many people are estimated to be living with aids?
UNAIDS estimated 36.9 million people living with HIV in 2018
HUMAN IMMUNODEFICIENCY VIRUS (HIV):
Epidemiology: How many people are estimated to be newly infected?
26,000 newly infected 2018
HUMAN IMMUNODEFICIENCY VIRUS (HIV):
Epidemiology: How many people are estimated to have died from aids related illnesses?
940 000 people died from AIDS-related illnesses in 2017.
HUMAN IMMUNODEFICIENCY VIRUS (HIV): HUMAN IMMUNODEFICIENCY VIRUS (HIV):
Epidemiology: How many people are estimated to have become infected with the HIV virus since the start of the epidemic?
77.3 million people have become infected with HIV since the start of the epidemic.
HUMAN IMMUNODEFICIENCY VIRUS (HIV): HUMAN IMMUNODEFICIENCY VIRUS (HIV):
Epidemiology: How many people are estimated to have died from AIDS-related illnesses since the start of the epidemic?
35.4 million people have died from AIDS-related illnesses since the start of the epidemic.
When infected with HIV, what happens to the immune system?
Immune system functions are compromised
When infected with HIV, what happens to individuals’ chance of getting infections?
Individual more susceptible to infections
HIV replication- What occurs?
Chronic, persistent destruction of infection-fighting cells, the CD4+ cells
HIV: Pathophysiology
Viral transmission, seroconversion, and acute viral infection
HIV: Pathophysiology
How are the chronic infections?
Asymptomatic chronic infection
Symptomatic chronic infection
HIV: Pathophysiology
HIV can turn into what if left untreated?
Acquired immune deficiency syndrome (AIDS)
HIV CLINICAL MANIFESTIONS
Fever
Cough
Weakness
Nausea/vomiting
Diarrhea
Dysphagia
Forgetfulness
Skin lesions
Shortness of breath
Headache
Vision changes
Pain
Night sweats
Lymphadenopathy
HIV MANAGEMENT:
What assesses for antibodies to the HIV virus?
- Diagnostic or screening tests assess for antibodies to the HIV virus
HIV MANAGEMENT:
Diagnostic or screening tests assess for antibodies to the HIV virus: What are the two types?
- Rapid tests
- ELISA (enzyme-linked immunoabsorbent assay) screening test
HIV MANAGEMENT:
Rapid tests do not require what?
Rapid tests do not require a laboratory to perform
HIV MANAGEMENT:
What does a negative screening test not require?
When should screening be repeated?
Negative screening test does not require confirmation (should repeat in 3 to 6 months)
HIV MANAGEMENT:
Negative screening test does not require confirmation (should repeat in 3 to 6 months); What is done?
HIV Western blot
HIV Western blot
a laboratory test that separates blood proteins and detects HIV antibodies to confirm or contest an HIV diagnosis
HIV:
Drug therapy: What is given prophylactically?
Prophylaxis- PreP (Truvada)
Antiretroviral therapy (ART)
Immunizations
HIV Prevention?
Testing for HIV
HIV: Treatment barriers?
Inadequate testing
Compliance with the treatment